BioViotica

Chaetoglobosin C

Name: Chaetoglobosin C
Brand: BioViotica
SKU: BVT-0460
Price: 265.00 CHF
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BVT-0460-M0011 mgCHF 265.00

Specifications / Handling

More Information
Product Details
Synonyms	(21,22-Dihydro-19-ketone)-chaetoglobosin A
Product Type	Chemical
Properties
Formula	C₃₂H₃₆N₂O₅
MW	528.7
CAS	50645-76-6
Source/Host Chemicals	Isolated from Chaetomium sp.
Purity Chemicals	≥97% (HPLC, NMR)
Appearance	White solid.
Solubility	Soluble in DMSO. Almost insoluble in water or usual organic solvents.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by BioViotica.
InChi Key	RIZAHVBYKWUPHQ-TZVWMMIDSA-N
Smiles	[H][C@]12[C@H](CC3=CNC4=CC=CC=C34)NC(=O)[C@]11C(=O)CCC(=O)C(=O)\C(C)=C/[C@@H](C)C\C=C\[C@@]1([H])[C@@H]1O[C@]1(C)[C@H]2C
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Protect from light.
Use/Stability	Stable for at least 1 year after receipt when stored at +4°C.
Documents
Safety Data Sheet	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Scientific Background Information

Product Description

Cytochalasan mycotoxin, derivative of chaetoglobosin A (Prod. No. BVT-0092).
Phytotoxic and antifungal compound.
Moderate cytotoxic compound.

Product-specific References

Isolation and structure determination of the mycotoxin chaetoglobosin C, a new [13]cytochalasin: J.P. Springer, et al.; Tetrahedron Lett. 17, 1355 (1976)
Chaetoglobosins, cytotoxic 10-(indol-3-yl)-[13]cytochalasans from Chaetomium spp. I. Production, isolation and some cytological effects of chaetoglobosins A-J: S. Sekita, et al.; Chem. Pharm. Bull. 30, 1609 (1982)
Chaetoglobosins, cytotoxic 10-(indol-3-yl)-[13]cytochalasans from Chaetomium spp. III. structures of chaetoglobosins C, E, F, G, and J: S. Sekita, et al.; Chem. Pharm. Bull. 30, 1629 (1982)
Chaetoglobosin U, a cytochalasan alkaloid from endophytic Chaetomium globosum IFB-E019: G. Ding, et al.; J. Nat. Prod. 69, 302 (2006)
Phytotoxin isolated from the culture broth of Chaetomium sp: C.-H. Lim, et al.; Han'guk Eungyong Sangmyong Hwahakhoeji 50, 316 (2007)
Bioactive metabolites produced by Chaetomium globosum, an endophytic fungus isolated from Ginkgo biloba: J.-C. Qin, et al.; Bioorg. Med. Chem. Lett. 19, 1572 (2009)
Cytotoxic 10-(indol-3-yl)-[13]cytochalasans from the fungus Chaetomium elatum ChE01: S. Thohinung, et al.; Arch. Pharm. Res. 33, 1135 (2010)
Cytotoxic chaetoglobosins from the endophyte Chaetomium globosum: J. Zhang, et al.; Planta Med. 76, 1910 (2010)
Evaluation of microbial elicitors to induce plant immunity for tomato wilt: S. Kasem, et al.; Afr. J. Microbiol. Res. 7, 1993 (2013)
Antifungal metabolites produced by Chaetomium globosum No.04, an endophytic fungus isolated from Ginkgo biloba: G. Zhang, et al.; Indian J. Microbiol. 53, 175 (2013)
Chaetoglobosins from Chaetomium globosum, an endophytic fungus in Ginkgo biloba, and their phytotoxic and cytotoxic activities: H. Li, et al.; J. Agr. Food Chem. 62, 3734 (2014)

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