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Innaxon - Innate Immunity to Life


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The Experts for TLR agonists and antagonists


Innaxon develops and manufactures defined “Immunoceuticals” of the highest activity and purity for pre-clinical research and development applications for vaccine adjuvants and immuno-therapy. Our unique biological and synthetic Toll-like Receptor (TLR) ligands are well-characterized and effective biological response modifiers of inappropriate or disproportionate immune responses.


Adipogen International, Inc. provides Innaxon Products worldwide. For product inquiries contact: info@adipogen.com

For the corporate website see: www.innaxon.co.uk
  TLR4-MD2 Complex


 

The TLR4/LPS Experts – Highest Quality

• TLRpure™: Qualified Purity & Activity
• High potency TLR4-specific ligands
• Ultrapure (no detectable protein, RNA & DNA)
• Tested on TLR4 KO murine macrophages
• Standardized aqueous sterile solutions
• Ready-to-use Lipid A and MPLA solutions
• No purification or hazardous solubilization
• BULK available for in vivo studies
• Excellent lot-to-lot reproducibility
• Broadest LPS chemotype and serotypeselection
• Unique TLR4 Explorer Sets™
• More than 40 years of experience in LPSpurification & characterisation
  


The ODN Experts – Competitive Prices 

• Endotoxin-free and sterile
• Potent TLR9 ligands
• Tested on TLR9 KO murine macrophages
• BULK available for in vivo studies
• ddWater Endotoxin-free (sterile) included
• Unique TLR9 Explorer Sets™
• Inhibitory ODNs (iODNs) available
• Negative ODN Controls available


IAXO Compounds – Unique! 

• Novel small molecule CD14/TLR4 antagonists
• Potent pre-clinical in vivo activity
• Inactive control compounds available





Product Overview of all Innaxon Products


Lipopolysaccharides (LPS)


PID Product Name         Size
S-Form LPS


 
IAX-100-009 
                   
LPS (Universal) from S. abortus equi (S-form) TLRpure™ Sterile Solution
THE STANDARD           
  500 µg
     1 mg
       5 x 1 mg
IAX-100-006

LPS from E. coli O8:K27 (S-form) TLRpure™ Sterile Solution

500 µg
1 mg
5 x 1 mg
IAX-100-012

LPS from E. coli O111:B4 (S-form) TLRpure™ Sterile Solution

500 µg
1 mg
5 x 1 mg
IAX-100-013

LPS from E. coli O55:B5 (S-form) TLRpure™ Sterile Solution

500 µg
1 mg
5 x 1 mg
IAX-100-019

LPS from S. enteritidis (S-form) TLRpure™ Sterile Solution

500 µg
1 mg
5 x 1 mg
IAX-100-020

LPS from S. minnesota (S-form) TLRpure™ Sterile Solution

500 µg
1 mg
5 x 1 mg
IAX-100-011

LPS from S. typhimurium (S-form) TLRpure™ Sterile Solution

500 µg
1 mg
5 x 1 mg
IAX-100-009B

LPS from S. abortus equi (S-form) Biotin TLRpure™ Sterile Solution

250 µg
500 µg
R-Form LPS
 
IAX-100-007

LPS from E. coli R515 (Re) TLRpure™ Sterile Solution
THE STANDARD
500 µg
1 mg
5 x 1 mg
IAX-100-008

LPS from S. minnesota R595 (Re) TLRpure™ Sterile Solution
THE STANDARD
500 µg
1 mg
5 x 1 mg
IAX-100-010

LPS from E. coli EH100 (Ra) TLRpure™ Sterile Solution

500 µg
1 mg
5 x 1 mg
IAX-100-016

LPS from S. minnesota R60 (Ra) TLRpure™ Sterile Solution

500 µg
1 mg
IAX-100-015

LPS from S. minnesota R345 (Rb) TLRpure™ Sterile Solution

500 µg
1 mg
5 x 1 mg
IAX-100-017

LPS from S. minnesota R5 (Rc) TLRpure™ Sterile Solution

500 µg
1 mg
5 x 1 mg
IAX-100-014

LPS from E. coli J5 (Rc) TLRpure™ Sterile Solution

500 µg
1 mg
5 x 1 mg
IAX-100-018

LPS from S. minnesota R7 (Rd1) TLRpure™ Sterile Solution

500 µg
1 mg
5 x 1 mg
IAX-100-021

LPS from S. minnesota R3 (Rd2) TLRpure™ Sterile Solution

500 µg
1 mg
5 x 1 mg
Lipid A and MLPA
 
IAX-100-004

Lipid A from E. coli R515 (Re) TLRpure™ Sterile Solution

250 µg
500 µg
1 mg
IAX-100-004DF Lipid A from E. coli R515 (Re) TLRpure Powder 1 mg
5 mg
IAX-100-001

Lipid A from S. minnesota R595 (Re) TLRpure™ Sterile Solution

250 µg
500 µg
1 mg
IAX-100-001DF Lipid A from S. minnesota R595 (Re) TLRpure Powder 1 mg
5 mg
IAX-100-002

MPLA from S. minnesota R595 (Re) TLRpure™ Sterile Solution

250 µg
500 µg
1 mg
IAX-100-002DF MPLA from S. minnesota R595 (Re) TLRpure Powder 1mg
5mg
IAX-100-003

MPLA from E. coli R515 (Re) TLRpure™ Sterile Solution

250 µg
500 µg
1 mg
IAX-100-003DF MPLA from E. coli R515 (Re) TLRpure Powder 1 mg
5 mg


Endotoxin-free Oligonucleotides


PID Product Name         Size
ODNs


 
IAX-200-001
                   
ODN 1668 (Type B) Endotoxin-free (sterile)
THE STANDARD           
  100 µg
     1 mg
3 x 1 mg
IAX-200-002

ODN 1826 (Type B) Endotoxin-free (sterile)
THE STANDARD
100 µg
1 mg
3 x 1 mg
IAX-200-005

ODN 2216 (Type A) Endotoxin-free (sterile)
THE STANDARD
100 µg
1 mg
3 x 1 mg
IAX-200-003

ODN 1585 (Type A) Endotoxin-free (sterile)

100 µg
1 mg
3 x 1 mg
IAX-200-004

ODN M362 (Type C) Endotoxin-free (sterile)

100 µg
1 mg
IAX-200-006

ODN 2006 (Type B) Endotoxin-free (sterile)

100 µg
1 mg
3 x 1 mg
IAX-200-007

ODN 2395 (Type C) Endotoxin-free (sterile)

100 µg
1 mg
 3 x 1 mg
IAX-200-024

AT-ODN-1 Endotoxin-free (sterile)

100 µg

IAX-200-025

AT-ODN-2 Endotoxin-free (sterile)

100 µg

IAX-200-026

AT-ODN-3 Endotoxin-free (sterile)

100 µg

iODNs
 
IAX-200-050

iODN (inhibitory ODN) 2088 Endotoxin-free (sterile)

100 µg
1 mg
3 x 1 mg
IAX-200-051

iODN (inhibitory ODN) (ttaggg)4 Endotoxin-free (sterile)

100 µg
1 mg
3 x 1 mg
IAX-200-052

G-type iODN (inhibitory ODN) Endotoxin-free (sterile)

100 µg
1 mg
IAX-200-053

Mini-iODN (inhibitory ODN) Endotoxin-free (sterile)

100 µg
1 mg
IAX-200-054

Mega-iODN (inhibitory ODN) Endotoxin-free (sterile)

100 µg
1 mg
IAX-200-055

Duo-iODN (inhibitory ODN) Endotoxin-free (sterile)

100 µg
1 mg
Controls
   
IAX-200-200

ODN 1720 (Control for ODN 1668) Endotoxin-free (sterile) 

100 µg

IAX-200-201

ODN 1982 (Control for ODN 1826) Endotoxin-free (sterile) 

100 µg

IAX-200-202

Neutral-ODN (Control for iODNs) Endotoxin-free (sterile)

100 µg
1 mg
3 x 1 mg
IAX-200-203

ODN 2118 (Control for ODN 1585) Endotoxin-free (sterile) 

100 µg

IAX-200-204

ODN M383 (Control for ODN M362) Endotoxin-free (sterile) 

100 µg

IAX-200-205

ODN 2243 (Control for ODN 2216) Endotoxin-free (sterile) 

100 µg

IAX-200-206

ODN 2137 (Control for ODN 2006) Endotoxin-free (sterile) 

100 µg



Endotoxin-free Immunoceuticals


PID Product Name         Size
IAX-200-021

                   
Poly(I:C) Endotoxin-free (sterile)


 2 mg
5 mg
10 mg
IAX-200-022

Poly(A:T) Endotoxin-free (sterile)

50 µg

IAX-200-023

Oligo(A:T) Endotoxin-free (sterile)

50 µg

IAX-200-101

Trehalose 6,6’-dimycolate (TDM) [Cord Factor] Endotoxin-free (sterile)

1 mg
 
IAX-200-102

Hyaluronic Acid Oligosaccharides (<1.5kDa) Endotoxin-free Sterile Solution

250 µg
 
IAX-200-103

Hyaluronic Acid Oligosaccharides (1.5-3.0kDa) Endotoxin-free Sterile Solution

250 µg





TLR Explorer Sets


PID Product Name         Size
IAX-300-001 
                   
TLR4 Agonist (Salmonella) Explorer Set I TLRpure
(S-LPS, R-LPS, MPLA)

 1 Set

IAX-300-002

TLR4 Agonist (Salmonella) Explorer Set II TLRpure
(S-LPS, R-LPS, Lipid A, MPLA)

1 Set

IAX-300-003

TLR4 Agonist (E. coli) Explorer Set I TLRpure
(S-LPS, R-LPS, MPLA)

1 Set

IAX-300-004

TLR4 Agonist (E. coli) Explorer Set II TLRpure
(S-LPS, R-LPS, Lipid A, MPLA)

1 Set

IAX-300-005

iODN (inhibitory ODN) Explorer Set I Endotoxin-free
(4 class I iODNs + Control ODN)

1 Set

IAX-300-006

iODN (inhibitory ODN) Explorer Set II Endotoxin-free
(6 class I / II iODNs + Control ODN)

1 Set

IAX-300-007

TLR9 Agonist (human) Explorer Set Endotoxin-free
(CpG ODN Type A, B and C)

1 Set

IAX-300-008

TLR9 Agonist (mouse) Explorer Set Endotoxin-free
(CpG ODN Type A, B and C)

1 Set



IAXO Compounds


PID Product Name         Size
IAX-600-001 
                   
IAXO-101 (CD14/TLR4 Antagonist) (synthetic)

 1 mg
5 mg
IAX-600-002

IAXO-102 (CD14/TLR4 Antagonist) (synthetic)

1 mg
5 mg
IAX-600-003

IAXO-103 (CD14/TLR4 Antagonist) (synthetic)

1 mg
5 mg
IAX-600-004

IAXO-201 (Control for IAXO-102)

1 mg

IAX-600-005

IAXO-202 (Control for IAXO-101/IAXO-103)

1 mg



Accessories


PID Product Name         Size
IAX-900-001 
                   
PBS Endotoxin-free (sterile)

 1.5 ml
10 ml
IAX-900-002

ddWater Endotoxin-free (sterile)

1.5 ml
10 ml
IAX-900-003

Physiological Saline [Sodium Chloride 0.9%] Sterile Solution

1.5 ml
10 ml 



More Information

 

Product Flyer

Download the new Innaxon 3 for 2 ODN Promotion Flyer and SAVE some money!   Innaxon 3 for 2 Promotion

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Check out all Innaxon Products and a lot of Technical Notes!    Innate Immunity Brochure 2013

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Please contact us at info@adipogen.com to receive a print copy of the new Innaxon Product Flyer! Also available for download!












  Innaxon Product Flyer

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