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SynKinase
VTX-27
CHF 0.00
In stock
SYN-1206-M0011 mgCHF 312.00
SYN-1206-M0055 mgCHF 837.00
SYN-1206-M01010 mgCHF 1'348.00
SYN-1206-M05050 mgINQ
SYN-1206-M100100 mgINQ
| Product Details | |
|---|---|
| Synonyms | VTX27 |
| Product Type | Chemical |
| Properties | |
| Formula | C20H24ClFN6O |
| MW | 418.9 |
| CAS | 1321924-70-2 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: PKCθ Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | HXWARSZQGAFXJM-MGPUTAFESA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
VTX-27 is a potent and selective inhibitor of the PKCθ enzyme, with over 1000-fold against classical isoforms and over 10000-fold against atypical isoforms.
Product References
- Design and optimization of selective protein kinase C θ (PKCθ) inhibitors for the treatment of autoimmune diseases: J.M. Jimenez, et al.; J. Med. Chem. 56, 1799 (2013)
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