SynKinase

LDK378

As low as CHF 85.00

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SYN-1199-M0011 mgCHF 85.00

SYN-1199-M0055 mgCHF 128.00

SYN-1199-M01010 mgCHF 170.00

SYN-1199-M05050 mgCHF 553.00

SYN-1199-M100100 mgCHF 922.00

Specifications / Handling

More Information
Product Details
Synonyms	LDK-378
Product Type	Chemical
Properties
Formula	C₂₈H₃₆ClN₅O₃S
MW	558.1
CAS	1032900-25-6
Purity Chemicals	≥95%
Appearance	Solid.
Solubility	Soluble in DMSO (heat) or ethanol.
Declaration	Manufactured by SynKinase.
Other Product Data	Target: ALK \| Kinase Group: RTK \| Substrate: Tyrosine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	VERWOWGGCGHDQE-UHFFFAOYSA-N
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product Description

LDK378 is potent inhibitor against ALK with IC(50) of 0.2nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.

Product-specific References

Targeting Anaplastic Lymphoma Kinase in Lung Cancer: A.T. Shaw & B. Solomon; Clin. Cancer Res. 17, 2081 (2011)

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