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anti-Malondialdehyde [MDA], mAb (1F83)

JAI-MMD-030N 30 µg INQ
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Additional Information

Properties
Clone 1F83
Isotype Mouse IgG2aλ
Immunogen/Antigen MDA-modified keyhole-lympet hemocyanine.
Application Immunohistochemistry: Recommended concentration is 0.5-1μg/mL on paraffin sections.
Crossreactivity All, Human
Specificity Recognizes MDA-modified proteins (especially DHP-lysine).
Purity Detail Protein A purified.
Formulation Frozen liquid. Contains 10mM PBS, 0.1% NaN3 and 0.5% BSA.
Other Product Data Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Origin Manufactured by JaICA.
Product Type Monoclonal Antibody
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 3 years after receipt when stored at -20°C.

Product Description

Malondialdehyde (MDA) is one of the major aldehyde derive from lipid peroxidation. MDA is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with MDA and lysine residue leads to the formation of numerous numbers of adducts, such as dihydropyridine-lysine (DHP-lysine) type derivative.

Product References

  1. Immunochemical detection of a lipofuscin-like fluorophore derivered from malondialdehyde and lysine: S. Yamada, et al.; J. Lipid Res. 42, 1187 (2001)
Immunohistochemical staining of MDA-modified protein in atherosclerotic aorta using anti-MDA, mAb (1F83).
Immunohistochemical staining of MDA-modified protein in atherosclerotic aorta using anti-MDA, mAb (1F83).
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