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anti-Crotonaldehyde [CRA], mAb (82D3)

JAI-MCA-030N 30 µg INQ
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Additional Information

Properties
Clone 82D3
Isotype Mouse IgG2a
Immunogen/Antigen CRA-modified keyhole-lympet hemocyanine.
Application Immunohistochemistry: Recommended concentration is 0.5-1μg/mL on paraffin sections.
Crossreactivity All, Human
Specificity Recognizes CRA-modified proteins (especially CRA-lysine adducts).
Purity Detail Protein A purified.
Formulation Frozen liquid. Contains 10mM PBS, 0.1% NaN3 and 0.5% BSA.
Other Product Data Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Origin Manufactured by JaICA.
Product Type Monoclonal Antibody
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 3 years after receipt when stored at -20°C.

Product Description

Crotonaldehyde (CRA) is a representative carcinogenic aldehyde formed endogenously through lipid peroxidation. CRA is highly reactive aldehyde and reacts with lysine residue in protein. The reaction with CRA and lysine residue leads to the formation of numerous numbers of adducts.

Product References

  1. Endogenous formation of protein adducts with carcinogenic aldehydes: K. Ichihashi, et al.; J. Biol. Chem. 276, 23903 (2001)
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