Chemodex

Zinpyr-1

Name: Zinpyr-1
Brand: Chemodex
SKU: CDX-Z0001
Price: 1217.00 CHF
Availability: InStock

As low as CHF 233.00

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CDX-Z0001-M02020 mgCHF 233.00

CDX-Z0001-M125125 mgCHF 1’217.00

Specifications / Handling

More Information
Product Details
Synonyms	ZP-1; 4′,5′-Bis[bis(2-pyridylmethyl)aminomethyl]-2′,7′-dichlorofluorescein
Product Type	Chemical
Properties
Formula	C₄₆H₃₆Cl₂N₆O₅
MW	823.72
CAS	288574-78-7
Source/Host Chemicals	Synthetic.
Purity Chemicals	≥98% (HPLC)
Appearance	Salmon pink powder.
Solubility	Soluble in DMSO (1mg/ml).
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	QZKKSPLNXQJQRQ-UHFFFAOYSA-N
Smiles	OC1=C(CN(CC2=CC=CC=N2)CC2=NC=CC=C2)C2=C(C=C1Cl)C1(OC(=O)C3=C1C=CC=C3)C1=CC(Cl)=C(O)C(CN(CC3=CC=CC=N3)CC3=NC=CC=C3)=C1O2
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
Safety Data Sheet	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Scientific Background Information

Product Description

Membrane permeable fluorescein-based probe suitable for the fluorometric detection of Zn2+. In living cells Zinpyr-1 mainly stains the Golgi or a Golgi-associated vesicle. It undergoes a shift in excitation from 515 to 507nm with increasing zinc concentrations using an emission filter over 513-558nm. A stock solution of 1mM (823µg/ml) should be prepared to stain brain sections. This stock solution can be further diluted in 0.9% saline to get a working solution with a final concentration of 10-20μM.

Product-specific References

(1) G.K. Walkup, et al; JACS 122, 5644 (2000) | (2) S.C. Burdette, et al.; JACS 123, 7831 (2001) | (3) C.C. Woodproof, et al.; Chem. Biol. 11, 1659 (2004) | (4) M. Malavolta, et al.; Cytometry Part A 69A, 1043 (2006) | (5) S.A. Sinclair, et al.; New Phytologist 174, 39 (2007)

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