Opipramol

Specifications / Handling

More Information
Product Details
Synonyms	NSC 169867; BRN 0627076; 2-{4-[3-(5H-Dibenzo[b,f]azepin-5-yl)propyl]-1-piperazinyl}ethanol
Product Type	Chemical
Properties
Formula	C₂₃H₂₉N₃O
MW	363.5
CAS	315-72-0
RTECS	TL9100000
Source/Host Chemicals	Synthetic.
Purity Chemicals	≥98% (HPLC)
Appearance	Yellow powder.
Solubility	Soluble in chloroform.
Identity	Determined by NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	YNZFUWZUGRBMHL-UHFFFAOYSA-N
Smiles	OCCN1CCN(CCCN2C3=CC=CC=C3C=CC3=CC=CC=C23)CC1
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Keep cool and dry. Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Tricyclic antidepressant and anxiolytic compound. Acts as a high affinity sigma receptor agonist, primarily at the σ1 subtype, but also at the σ2 subtype with somewhat lower affinity. Shows a low to moderate antagonistic affinity for the D2, 5-HT2, H1, H2, and muscarinic acetylcholine receptors. H1 and H2 receptor antagonism account for its antihistamine effects, and muscarinic acetylcholine receptor antagonism is responsible for its anticholinergic properties.

Product References

(1) T.S. Rao, et al.; Neuropharmacology. 29, 1191 (1990) | (2) T.S. Rao, et al.; Neuropharmacology. 29, 1199 (1990) | (3) H.J. Moller, et al.; J. Clin. Psychopharmacol. 21,59 (2001) | (4) G. Holoubek & W.E. Muller; J. Neural Transm. 110, 1169 (2003) | (5) W.E. Muller, et al.; Pharmacopsychiatry 37, S189 (2004)

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