Chemodex

H-Met-AMC

Name: H-Met-AMC
Brand: Chemodex
SKU: CDX-M0113
Price: 156.00 CHF
Availability: InStock

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CDX-M0113-M100100 mgCHF 156.00

CDX-M0113-G0022 gCHF 1’209.00

Specifications / Handling

More Information
Product Details
Synonyms	L-Methionine-7-amido-4-methylcoumarin
Product Type	Chemical
Properties
Formula	C₁₅H₁₈N₂O₃S . C₂HF₃O₂
MW	420.4
CAS	94367-35-8
Source/Host Chemicals	Synthetic.
Purity Chemicals	≥98% (NMR)
Appearance	White to off-white powder.
Solubility	Soluble in DMSO.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	VSAUWUJWXBUSEU-YDALLXLXSA-N
Smiles	[O-]C(=O)C(F)(F)F.CSCC[C@H]([NH3+])C(=O)NC1=CC=C2C(C)=CC(=O)OC2=C1
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
Product Specification Sheet
Datasheet	Download PDF

Scientific Background Information

Product Description

H-Met-AMC (L-methionine-7-amido-4-methylcoumarin) is a fluorogenic substrate for methionine aminopeptidase 2 (MetAP2) and aminopeptidase N. This substrate is a useful tool for inhibitor screening and kinetic analysis. It has also been described to be useful as a substrate for calpains.

Product-specific References

(1) T. Sasaki et al.; J. Biol. Chem. 259, 12489 (1984) | (2) A. Marschner & C.D. Klein; Biochimie 115, 35 (2015) | (3) S.Y. Bhat, et al.; Int. J. Biol. Macromol. 115, 940 (2018)

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