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Chemodex
7-Methylguanine
Specifications / Handling
| Product Details | |
|---|---|
| Synonyms | N7-Methylguanine; NSC 193444; NSC 19647; 2-Amino-6-hydroxy-7-methylpurine; Epiguanine |
| Product Type | Chemical |
| Properties | |
| Formula | C6H7N5O |
| MW | 165.15 |
| CAS | 578-76-7 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White powder. |
| Solubility | Soluble in DMSO. |
| Identity | Determined by NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | FZWGECJQACGGTI-UHFFFAOYSA-N |
| Smiles | CN1C=NC2=C1C(=O)N=C(N)N2 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| Safety Data Sheet |
Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Scientific Background Information
Integral part of the cap structure of mRNA necessary for the attachment of the nucleic acids to the ribosome. Has binding affinity to guanine deaminase, an important metalloenzyme in purine catabolism. Found in urine of patients with malignant cancer, suggesting an important role.
(1) S.J. Kerr; Tumour Biol. 6, 115 (1985) | (2) C. Hanski & S.J. Kerr; Cell Tissue Res. 241, 203 (1985) | (3) H. Li, et al.; J. Mass. Spectrom. 44, 641 (2009) | (4) J. Fernandez, et al.; Bioorg. Med. Chem. 18, 6748 (2010)
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