MQAE | CAS 162558-52-3 - Order from Adipochem

Specifications / Handling

More Information
Product Details
Synonyms	1-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide
Product Type	Chemical
Properties
Formula	C₁₄H₁₆NO₃Br
MW	326.19
CAS	162558-52-3
Source/Host Chemicals	Synthetic.
Purity Chemicals	≥97% (TLC)
Appearance	Faintly red to brown powder
Solubility	Soluble in water, methanol or DMSO.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	DSLLHVISNOIYHR-UHFFFAOYSA-M
Smiles	[Br-].CCOC(=O)C[N+]1=CC=CC2=CC(OC)=CC=C12
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

MQAE is a fluorescent chloride ion indicator for chloride measurement in cells. MQAE is a fluorescent indicator that is quenched via collision with chloride. The probe is suitable for detection of chloride concentrations in liposomes, reconstituted membranes or in extracellular medium. As a UV-excitable indicator, it can be detected using an argon-ion laser for confocal microscopy and flow cytometry applications. MQAE has greater sensitivity than SPQ and higher fluorescence quantum yield. Spectral Data: λex 350nm; λem 460nm in 0.1 M borate pH 8.0 (quenching with Cl-).

Product References

(1) A.S. Verkman, et al.; Anal. Biochem. 178, 355 (1989) | (2) A.S. Verkman; Am. J. Physiol. 259, C375 (1990) | (3) C. Koncz, et al.; Am. J. Physiol. 267, H2114 (1994) | (4) C. Andersson, et al.; Microscopy Res. Tech. 59, 531 (2002) | (5) Z.F. Lai, et al.; Eur. J. Pharmacol. 482, 1 (2003) | (6) F. Munkonge, et al.; J. Cyst. Fibros. 3 Suppl. 2, 171 (2004) | (7) H. Miyazaka, et al.; Am. J. Phys. 292, F1411 (2007) | (8) R.W. Sabnis; Handbook of biological dyes and stains (2010) | (9) Y. Kovalchuk, et al.; Cold Spring Harb Protoc. 2012, 778 (2012)

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