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Chemodex
Difluoromethyl phenyl sulfone
102
CHF
CHF 102.00
In stock
CDX-D0401-GG252.5 gCHF 102.00
CDX-D0401-G01010 gCHF 299.00
| Product Details | |
|---|---|
| Synonyms | Phenyl difluoromethyl sulfone |
| Product Type | Chemical |
| Properties | |
| Formula | C7H6F2O2S |
| MW | 192.2 |
| CAS | 1535-65-5 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Colorless to light yellow semi-solid or solid. |
| Solubility | Soluble in chloroform. |
| Identity | Determined by NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | LRHDNAVPELLXDL-UHFFFAOYSA-N |
| Smiles | FC(F)S(=O)(=O)C1=CC=CC=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Building block for synthesis. Has been used for nucleophilic difluoro(phenylsulfonyl)methylation of carbonyls, reductive silylation and the preparation of trifluoro- and difluoromethylsilanes, fluoroalkylation/chloroalkylation of α,β-enones, arynes, acetylenic ketones and other Michael acceptors and difluoromethylation of primary alkyl halides . It is also used in preparation of α-difluoromethyl amines, anti-difluoropropanediols, β-difluoromethylated and β-difluoromethylenated alcohols and amines, difluoroalkenes, difluoromethyl alcohol derivatives and fluoromethylated vicinal ethylenediamines.
Product References
(1) G.K.S. Prakash, et al.; J. Org. Chem. 68, 4457 (2003) | (2) G.K.S. Prakash, et al.; Angew. Chem. 42, 5216 (2003) | (3) G.K.S. Prakash, et al.; Angew. Chem. 43, 5203 (2004) | (4) G.K.S. Prakash, et al.; Org. Lett. 6, 4315 (2004) | (5) Y. Li & J. Hu; Angew. Chem. 44, 5882 (2005) | (6) G.K.S. Prakash, et al.; Europ. J. Org. Chem. 11, 2218 (2005) | (7) C. Ni, et al.; Angew. Chem. 46, 786 (2007) | (8) J. Liu, et al.; J. Org. Chem. 72, 3119 (2007) | (9) C. Ni, et al.; J. Org. Chem. 73, 5699 (2008) | (10) M. Hu, et al.; J. Fluor. Chem. 155, 52 (2013)
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