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Laurdan

CDX-D0098-M050 50 mg INQ
CDX-D0098-M250 250 mg INQ
CDX-D0098-G001 1 g INQ
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Additional Information

Product Data
Synonyms N,N-Dimethyl-6-dodecanoyl-2-naphthylamine
Properties
Formula C24H35NO
MW 353.54
CAS 74515-25-6
Source/Host Synthetic.
Purity ≥97% (HPLC)
Appearance Light yellow solid.
Solubility Soluble in methanol, DMF or acetonitrile.
Identity Determined by 1H-NMR.
Origin Manufactured by Chemodex.
Other Product Data Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key JHDGGIDITFLRJY-UHFFFAOYSA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.

Product Description

N,N-Dimethyl-6-dodecanoyl-2-naphthylamine (Laurdan) is used as an environmentally sensitive probe for the labeling of plasma membranes. The lauroyl-sidechain integrates into the hydrophobic core of biological membranes, the polar fluorescent moiety is at level of the glycerol-backbone. Dipolar relaxation processes of the naphtylamine-moiety with neighboring polar molecules lead to wavelength-shifts of the emission-spectra. The physical state of the membrane and effects of temperature, cholesterol or ethanol on various membrane-systems have been monitored.

Product References

(1) S.S. Antollini et al.; Meth. Mol. Biol. 400, 531 (2007) | (2) Y.L. Zhang et al.; Biochem. Biophys. Res. Comm. 347(3), 838 (2006) | (3) L. Bagatolli et al.; Biochimica et Biophysica Acta 1325, 80 (1997) | (4) L.I. Hellgren et al.; Plant Physiol. Biochem. 34(4), 455 (1996) | (5) G. Weber et al.; Biochemistry 18(14), 3075 (1979)
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