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CDX-C0014-M025 25 mg INQ
CDX-C0014-M100 100 mg INQ
CDX-C0014-G001 1 g INQ
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Additional Information

Product Data
Synonyms 5-Carboxyfluorescein
Formula C21H12O7
MW 376.32
CAS 76823-03-5
Source/Host Synthetic.
Purity ≥99% (HPLC)
Appearance Yellow-orange solid.
Solubility Soluble in water, DMSO or DMF.
Identity Determined by 1H-NMR.
Origin Manufactured by Chemodex.
Other Product Data Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.

Product Description

The amine-reactive fluorescein derivatives are probably the most common fluorescent derivatization reagents for covalently labeling proteins. Carboxyfluorescein is better retained in cells than is fluorescein, its pKa of ~6.5 is lower than the cytosolic pH of most cells (pH ~6.8-7.4). Carboxyfluorescein is commonly employed as a polar tracer.

Product References

(1) R. Fischer et al., Bioconjugate Chem. 14, 653 (2003) | (2) E. Ralston et al., Biochim. Biophys. Acta, Biomembranes 649(1), 133 (1981)
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