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BioViotica
Fridamycin A
As low as
CHF 110.00
In stock
Only %1 left
BVT-0469-M0011 mgCHF 110.00
BVT-0469-M0055 mgCHF 325.00
Specifications / Handling
| Product Details | |
|---|---|
| Synonyms | Vineomycinone B2 |
| Product Type | Chemical |
| Properties | |
| Formula |
C25H26O10 |
| MW | 486.5 |
| CAS | 30270-05-4 |
| Source/Host Chemicals | Isolated from Streptomyces parvulus. |
| Purity Chemicals | ≥97% (HPLC, NMR) |
| Appearance | Yellow to orange solid. |
| Solubility | Soluble in DMSO. Sparingly soluble in methanol or acetone. |
| Identity | Determined by 1H-NMR and MS. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | LKLNNJGYAYDANM-VRSSYPSJSA-N |
| Smiles | [H][C@@]1(C[C@@H](O)[C@H](O)[C@@H](C)O1)C1=C(O)C2=C(C=C1)C(=O)C1=C(C=CC(C[C@@](C)(O)CC(O)=O)=C1O)C2=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. Store solutions at -20°C in the dark. |
| Documents | |
| Safety Data Sheet |
Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Scientific Background Information
Product Description
- C-glycosidic angucyclinone derivative.
- Antibiotic.
- Antitumor agent.
- Antibacterial agent.
- Isomer of fridamycin B (Prod. No. BVT-0470).
Product-specific References
- The structure of vineomycin B2: N. Imamura, et al.; J. Antibiot. 34, 1517 (1981)
- Fridamycine, Anthracyclin-analoge Antibiotica: P. Knicke; Ph. D. Thesis Univ. Goettingen (1984)
- Angucycline group antibiotics: J. Rohr & R. Thiericke; Nat. Prod. Rep. 9, 103 (1992)
- Synthetic anthracyclines from anthraquinones: R. Cambie, et al.; Austr. J. Chem. 45, 483 (1992)
- C-Aryl glycosides via tandem intramolecular benzyne-furan cycloadditions. Total synthesis of vineomycine B2 methyl ester: C.-L. Chen, et al.; JACS 128, 13696 (2006)
- Convergent de novo synthesis of vineomycinione B2 methyl ester: Q. Chen, et al.; Chem. Comm. 49, 6806 (2013)
- Total Synthesis of vineomycin B2: S. Kusumi, et al.; JACS 135, 15909 (2013)
- Angucycline antibiotics and its derivatives from marine-derived actinomycete streptomyces sp. A6H: Z. Hu, et al.; Nat. Prod. Res. 30, 2551 (2016)
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