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Fridamycin A

BVT-0469-M001 1 mg $90.00
BVT-0469-M005 5 mg $270.00
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Additional Information

Product Data
Synonyms Vineomycinone B2
Properties
Formula C25H26O10
MW 486.5
CAS 30270-05-4
Source/Host Chemicals Isolated from Streptomyces parvulus.
Purity ≥97% (HPLC, NMR)
Appearance Yellow to orange solid.
Solubility Soluble in DMSO. Sparingly soluble in methanol or acetone.
Identity Determined by 1H-NMR and MS.
Origin Manufactured by BioViotica.
InChi Key LKLNNJGYAYDANM-VRSSYPSJSA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. Store solutions at -20°C in the dark.
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Product Description

  • C-glycosidic angucyclinone derivative.
  • Antibiotic.
  • Antitumor agent.
  • Antibacterial agent.
  • Isomer of fridamycin B (Prod. No. BVT-0470).

Product References

  1. The structure of vineomycin B2: N. Imamura, et al.; J. Antibiot. 34, 1517 (1981)
  2. Fridamycine, Anthracyclin-analoge Antibiotica: P. Knicke; Ph. D. Thesis Univ. Goettingen (1984)
  3. Angucycline group antibiotics: J. Rohr & R. Thiericke; Nat. Prod. Rep. 9, 103 (1992)
  4. Synthetic anthracyclines from anthraquinones: R. Cambie, et al.; Austr. J. Chem. 45, 483 (1992)
  5. C-Aryl glycosides via tandem intramolecular benzyne-furan cycloadditions. Total synthesis of vineomycine B2 methyl ester: C.-L. Chen, et al.; JACS 128, 13696 (2006)
  6. Convergent de novo synthesis of vineomycinione B2 methyl ester: Q. Chen, et al.; Chem. Comm. 49, 6806 (2013)
  7. Total Synthesis of vineomycin B2: S. Kusumi, et al.; JACS 135, 15909 (2013)
  8. Angucycline antibiotics and its derivatives from marine-derived actinomycete streptomyces sp. A6H: Z. Hu, et al.; Nat. Prod. Res. (Epub ahead of print) (2016)
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