BioViotica

Cytochalasin J

Name: Cytochalasin J
Brand: BioViotica
SKU: BVT-0450
Price: 115.00 CHF
Availability: InStock

As low as CHF 115.00

In stock

Only %1 left

BVT-0450-M0011 mgCHF 115.00

Specifications / Handling

More Information
Product Details
Synonyms	Deacetylcytochalasin H; Kodocytochalasin 2; Paspalin P II
Product Type	Chemical
Properties
Formula	C₂₈H₃₇NO₄
MW	451.6
CAS	53760-20-6
RTECS	HA5320000
Source/Host Chemicals	Isolated from Phomopsis sp.
Purity Chemicals	≥98% (NMR)
Appearance	White solid.
Solubility	Soluble in DMSO or water.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by BioViotica.
InChi Key	UKQNIEMKORIOQM-ITYZSRHZSA-N
Smiles	[H]C12[C@H](CC3=CC=CC=C3)NC(=O)[C@@]11[C@@H](\C=C\C[C@H](C)C[C@](C)(O)\C=C\[C@H]1O)[C@H](O)C(=C)[C@H]2C
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Protect from light when in solution.
Use/Stability	Stable for at least 1 year after receipt when stored at +4°C.
Documents
Safety Data Sheet	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product Description

Mycotoxin.
Phytotoxic and cytotoxic agent.
Immunosuppressive activity.
Affects chromosome congression and spindle microtubule organization in PtK1 cells.
Actin and myosin inhibitor.

Product-specific References

Isolation and biological properties of deacetylcytochalasin H from Phomopsis sp.: R.J. Cole, et al.; J. Agric. Food Chem. 29, 205 (1981)
A new immunosuppressive cytochalasin isolated from a Pestalotia sp.: N.S. Burres, et al.; J. Antibiot. 45, 1367 (1992)
Cytochalasin J affects chromosome congression and spindle microtubule organization in PtK1 cells: J.A. Snyder, et al.; Cell Motil. Cytoskel. 32, 245 (1995)
The effect of cytochalasin J on kinetochore structure in PTK1 cells is mitotic cycle dependent: G.A. Wrench & J.A. Snyder; Cell Biol. Int. 25, 815 (2001)
Redistribution of motor proteins by cytochalasin J treatment: R.W. Robinson & J.A. Snyder; Cell Biol. Int. 27, 665 (2003)
Colocalization studies of Arp1 and p150Glued to spindle mircotubules during mitosis: the effect of cytochalasin J on the organization of microtubules and motor proteins in PtK1 cells: R.W. Robinson, et. al.; Cell Biol. Int. 30, 631 (2006)
Cytotoxic cytochalasin metabolites of endophytic Endothia gyrosa: S. Xu, et al.; Chem. Biodiv. 6, 739 (2009)
Both actin and myosin inhibitors affect spindle architecture in PtK1 cells: J.A. Snyder, et al.; Protoplasma 240, 57 (2010)

Call	+41 61 926 6040
Fax	+41 61 926 6049