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BioViotica
Cytochalasin J
115
CHF
CHF 115.00
In stock
BVT-0450-M0011 mgCHF 115.00
| Product Details | |
|---|---|
| Synonyms | Deacetylcytochalasin H; Kodocytochalasin 2; Paspalin P II |
| Product Type | Chemical |
| Properties | |
| Formula |
C28H37NO4 |
| MW | 451.6 |
| CAS | 53760-20-6 |
| RTECS | HA5320000 |
| Source/Host Chemicals | Isolated from Phomopsis sp. |
| Purity Chemicals | ≥98% (NMR) |
| Appearance | White solid. |
| Solubility | Soluble in DMSO or water. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | UKQNIEMKORIOQM-ITYZSRHZSA-N |
| Smiles | [H]C12[C@H](CC3=CC=CC=C3)NC(=O)[C@@]11[C@@H](\C=C\C[C@H](C)C[C@](C)(O)\C=C\[C@H]1O)[C@H](O)C(=C)[C@H]2C |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light when in solution. |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Mycotoxin.
- Phytotoxic and cytotoxic agent.
- Immunosuppressive activity.
- Affects chromosome congression and spindle microtubule organization in PtK1 cells.
- Actin and myosin inhibitor.
Product References
- Isolation and biological properties of deacetylcytochalasin H from Phomopsis sp.: R.J. Cole, et al.; J. Agric. Food Chem. 29, 205 (1981)
- A new immunosuppressive cytochalasin isolated from a Pestalotia sp.: N.S. Burres, et al.; J. Antibiot. 45, 1367 (1992)
- Cytochalasin J affects chromosome congression and spindle microtubule organization in PtK1 cells: J.A. Snyder, et al.; Cell Motil. Cytoskel. 32, 245 (1995)
- The effect of cytochalasin J on kinetochore structure in PTK1 cells is mitotic cycle dependent: G.A. Wrench & J.A. Snyder; Cell Biol. Int. 25, 815 (2001)
- Redistribution of motor proteins by cytochalasin J treatment: R.W. Robinson & J.A. Snyder; Cell Biol. Int. 27, 665 (2003)
- Colocalization studies of Arp1 and p150Glued to spindle mircotubules during mitosis: the effect of cytochalasin J on the organization of microtubules and motor proteins in PtK1 cells: R.W. Robinson, et. al.; Cell Biol. Int. 30, 631 (2006)
- Cytotoxic cytochalasin metabolites of endophytic Endothia gyrosa: S. Xu, et al.; Chem. Biodiv. 6, 739 (2009)
- Both actin and myosin inhibitors affect spindle architecture in PtK1 cells: J.A. Snyder, et al.; Protoplasma 240, 57 (2010)
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