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Roquefortine C

BVT-0425-C500 500 µg $80.00
BVT-0425-M001 1 mg $125.00
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Additional Information

Product Data
Synonyms NSC292134
Properties
Formula C22H23N5O2
MW 389.5
CAS 58735-64-1
RTECS UQ4730500
Source/Host Chemicals Isolated from Penicillium sp.
Purity ≥98% (HPLC, NMR)
Appearance White to off-white solid.
Solubility Soluble in DMSO, methanol, 100% ethanol, dimethylformamide, acetone, chloroform or dichloromethane.
Identity Determined by 1H-NMR.
Origin Manufactured by BioViotica.
InChi Key SPWSUFUPTSJWNG-JJUKSXGLSA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
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Product Description

  • Potent neurotoxin.
  • Mycotoxin.
  • Tremorgenic.
  • Gram-positive bacteria growth inhibitor.
  • Cytochrome p450 inhibitor.
  • Lymphocyte proliferation inhibitor.
  • Cytotoxic.

Product References

  1. Isolation of festuclavine and three new indole alkaloids, roquefortine A, B and C from the cultures of Penicillium roqueforti: S. Ohmomo, et al.; Agric. Biol. Chem. 39, 1333 (1975)
  2. Roquefortine and isofumigaclavine A, metabolites from Penicillium roqueforti: P.M. Scott, et al.; Experientia 32, 140 (1976)
  3. Identification of roquefortine C produced by Penicillium roqueforti: S. Ohmomo et al.; Agric. Biol. Chem. 41, 2097 (1977)
  4. Antimicrobial action of roquefortine: B. Kopp-Holtwiesche & H.J. Rehm; J. Environ. Pathol. Toxicol. Oncol. 10, 41 (1990)
  5. MS/MS screen for the tremorgenic mycotoxins roquefortine and penitrem A: W.E. Braselton & P.C. Rumler; J. Vet. Diagn. Invest. 8, 515 (1996)
  6. Molecular requirements for inhibition of cytochrome p450 activities by roquefortine: C. Aninat, et al.; Chem. Res. Toxicol. 14, 1259 (2001)
  7. The effects of the Penicillium mycotoxins citrinin, cyclopiazonic acid, ochratoxin A, patulin, penicillic acid, and roquefortine C on in vitro proliferation of porcine lymphocytes: M. Keblys, et al.; Mycopathologia 158, 317 (2004)
  8. Combined effects of selected Penicillium mycotoxins on in vitro proliferation of porcine lymphocytes: A. Bernhoft, et al.; Mycopathologia 158, 441 (2004)
  9. Cytotoxicity of occupationally and environmentally relevant mycotoxins: J. Bunger, et al.; Toxicology 202, 199 (2004)
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