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Butylcycloheptylprodigiosin

BVT-0423-C250 250 µg $85.00
BVT-0423-M001 1 mg $255.00
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Additional Information

Product Data
Synonyms Butyl-ortho-cycloheptylprodiginine
Properties
Formula C25H33N3O
MW 391.6
CAS 352304-41-7
Source/Host Chemicals Isolated from Streptomyces parvulus.
Purity ≥93% (NMR)
Appearance Red solid.
Solubility Soluble in DMSO, methanol, acetone or chloroform.
Identity Determined by 1H-NMR.
Origin Manufactured by BioViotica.
InChi Key ZBKQNSZMEUHFKN-JTOYMXJDSA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Documents
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Product Description

  • Tripyrrolic pigment like prodigiosin.
  • Antimalarial agent.
  • Anticancer agent with multiple modes of action.
  • Immunosuppressant in non-toxic concentrations.
  • Bone resorption inhibitor.
  • Antiulcer agent.

Product References

  1. A new prodiginine (prodigiosin-like) pigment from Streptomyces. Antimalarial activity of several prodiginines: N. N. Gerber; J. Antibiot. 28, 194 (1975)
  2. Chemistry and biology of roseophilin and the prodigiosin alkaloids: a survey of the last 2500 years: A. Furstner; Angew. Chem. Int. Ed. 42, 3582 (2003)
  3. The biosynthesis and regulation of bacterial prodiginines: N. R. Williamson, et al.; Nat. Rev. Microbiol. 4, 887 (2006) (Review)
  4. Total synthesis, molecular editing and evaluation of a tripyrrolic natural product: the case of 'butylcycloheptylprodigiosin': A. Furstner, et al.; Chem. Eur. J. 13, 1929 (2007)
  5. A concise synthesis of butylcycloheptylprodigiosin: J. T. Reeves; Org. Lett. 9, 1879 (2007)
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