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Chaetoviridin A

BVT-0419-M001 1 mg $115.00
BVT-0419-M005 5 mg $430.00
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Additional Information

Product Data
Synonyms CCRIS 7226
Properties
Formula C23H25ClO6
MW 432.9
CAS 128252-98-2
Source/Host Chemicals Isolated from Chaetomium sp.
Purity ≥96% (HPLC)
Appearance Yellow to orange powder.
Solubility Soluble in DMSO, methanol, chloroform or acetone.
Identity Determined by 1H-NMR.
Origin Manufactured by BioViotica.
InChi Key HWSQVPGTQUYLEQ-CCBHEJLASA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
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Product Description

  • Azaphilone antibiotic.
  • Antifungal compound (phytopathogenic fungi).
  • Cholesteryl ester transfer protein (CETP) inhibitor. Improves blood lipid levels.
  • Monoamine oxidase inhibitor.

Product References

  1. Four new azaphilones from Chaetomium globosum var. flavor-viridae: M. Takahashi, et al.; Chem. Pharm. Bull. 38, 625 (1990)
  2. Structure-specific inhibition of cholesteryl ester transfer protein by azaphilones: H. Tomoda, et al.; J. Antibiot. 52, 160 (1999)
  3. Antifungal activity against plant pathogenic fungi of chaetoviridins isolated from Chaetomium globosum: J.-H. Park, et al.; FEMS Microbiol. Lett. 252, 309 (2005)
  4. Bis-spiro-azaphilones and azaphilones from the fungi Chaetomium cochliodes VTh01 and C. cochliodes CTh05: N. Phonkerd, et al.; Tetrahedron 64, 9636 (2008)
  5. Azaphilones, a class of fungal metabolites with diverse biological activities: N. Osmanova, et al.; Phytochem. Rev. 9, 315 (2010)
  6. Azaphilones from the endophyte Chaetomium globosum: W. S. Borges, et al.; J. Nat. Prod. 74, 1182 (2011)
  7. Identification and characterization of the chaetoviridin and chaetomugilin gene cluster in Chaetomium globosum: J. M. Winter, et al.; JACS 134, 17900 (2012)
  8. New azaphilones from Chaetomium globosum isolated from the built environment: D. R. McMullin, et al.; Tetrahedron Lett. 54, 568 (2013)
  9. Potentially harmful secondary metabolites produced by indoor Chaetomium species on artificially and naturally contaminated building materials: I. Dosen, et al.; Indoor Air 27, 34 (2017)
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