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Aurantimycin A

BVT-0398-M001 1 mg $28.00
BVT-0398-M005 5 mg $75.00
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Additional Information

Properties
Formula C38H64N8O14
MW 857.0
CAS 162478-50-4
Source/Host Chemicals Isolated from Streptomyces aurantiacus JA 4570.
Purity ≥98% (HPLC)
Appearance Off-white solid.
Solubility Soluble in chloroform, dichloromethane or DMSO. Poorly soluble in water.
Identity Determined by 1H-NMR.
Origin Manufactured by BioViotica.
InChi Key JSVPJXYQXDNLRD-NSCUIBACSA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
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Product Description

  • Depsipeptide antibiotic.
  • Active against Gram-positive bacteria.
  • Cytotoxic agent.
  • Nematocide activity.
  • Antiulcer agent.
  • Anti-inflammatory drug (C5a antagonist).

Product References

  1. Aurantimycins, new depsipeptide antibiotics from Streptomyces aurantiacus IMET 43917: U. Graefe, et al.; J. Antibiot. 48, 119 (1995)
  2. Formation of membrane pores by aurantimycins A and B, new lipopeptide antibiotics from Streptomyces aurantiacus: P. Grigoriev, et al.; Bioelectrochem. Bioenerget. 36, 57 (1995)
  3. Pharmacological actions of a new synthetic cyclodepsipeptide, the A83586C-citropeptin hybrid, on complement C5a and G-proteins: E.-S. K. Assem, et al.; Inflamm. Res. 57, 21 (2008)
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