BioViotica

Rubrofusarin

Name: Rubrofusarin
Brand: BioViotica
SKU: BVT-0395
Price: 130.00 CHF
Availability: InStock

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BVT-0395-M0011 mgCHF 130.00

BVT-0395-M0055 mgCHF 395.00

Specifications / Handling

More Information
Product Details
Synonyms	NSC 258316
Product Type	Chemical
Properties
Formula	C₁₅H₁₂O₅
MW	272.3
CAS	3567-00-8
Source/Host Chemicals	Isolated from Fusarium graminearum.
Purity Chemicals	≥98% (HPLC)
Appearance	Orange needles.
Solubility	Soluble in DMSO. Sparingly soluble in usual organic solvents.
Identity	Determined by ¹H-NMR and UV.
Declaration	Manufactured by BioViotica.
InChi Key	FPNKCZKRICBAKG-UHFFFAOYSA-N
Smiles	COC1=CC2=C(C(O)=C1)C(O)=C1C(=O)C=C(C)OC1=C2
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light when in solution.
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Documents
Safety Data Sheet	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Scientific Background Information

Product Description

Monomer of aurofusarin.
Mycotoxin.
Anticancer and antimycobacterial compound in vivo.
Moderate tyrosinase inhibitor.
Anti-estrogenic.

Product-specific References

Structure of rubrofusarin: G.H. Stout, et al.; Chem. Indust. 1961, 289 (1961).
Metabolic products of fungi. XXV. Synthesis of rubrofusarin and its derivatives: S. Shibata, et al.; Chem. Pharm. Bul.l (Tokyo) 15, 1757 (1967)
The biosynthesis of rubrofusarin, a polyketide naphthopyrone from Fusarium culmorum: F.J. Leeper & J. Staunton; J. Chem. Soc. Perkin 1 1984, 2919 (1984).
Biometic syntheses of the polyketide fungal metabolites alternariol and rubrofusarin: C. Abell, et al.; J. Chem. Soc. Chem. Comm. 1986, 15 (1986)
Phenolic constituents of Cassia seeds and antibacterial effect of some naphthalenes and anthraquinones on methicillin-resistant St. aureus: T. Hatano, et al.; Chem. Pharm. Bull. 47, 1121 (1999)
A new naphthopyrone derivative from Cassia quinquangulata and structural revision of quinquangulin and its glycosides: X.C. Li, et al.; J. Nat. Prod. 64, 1153 (2001)
Antimycobacterial naphthopyrones from Senna oblique: J.G. Graham, et al.; J. Nat. Prod. 67, 225 (2004)
Estrogenic and anti-estrogenic activities of Cassia tora phenolic constituents: A.M. El-Halawany, et al.; Chem. Pharm. Bull. (Tokyo) 55, 1476 (2007)
In vitro cytotoxicity of fungal spoiling maize silage: R.R. Rasmussen, et al.; Food Chem. Toxicol. 49, 31 (2010)
Three dimeric naphtho-γ-pyrones from the mangrove endophytic fungus Aspergillus tubingensis isolated from Pongamia pinnata: H.-B. Huang, et al.; Planta Med 76, 1888 (2010)
Two novel classes of enzymes are required for the biosynthesis of aurofusarin in Fusarium graminearum: R.J.N. Frandsen, et al.; J. Biol. Chem. 286, 10419 (2011)

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