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Rubrofusarin

BVT-0395-M001 1 mg $110.00
BVT-0395-M005 5 mg $330.00
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Additional Information

Product Data
Synonyms NSC 258316
Properties
Formula C15H12O5
MW 272.3
CAS 3567-00-8
Source/Host Chemicals Isolated from Fusarium graminearum.
Purity ≥98% (HPLC)
Appearance Orange needles.
Solubility Soluble in DMSO. Sparingly soluble in usual organic solvents.
Identity Determined by 1H-NMR and UV.
Origin Manufactured by BioViotica.
InChi Key FPNKCZKRICBAKG-UHFFFAOYSA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Documents
MSDS Download Document Download

Product Description

  • Monomer of aurofusarin.
  • Mycotoxin.
  • Anticancer and antimycobacterial compound in vivo.
  • Moderate tyrosinase inhibitor.
  • Anti-estrogenic.

Product References

  1. Structure of rubrofusarin: G.H. Stout, et al.; Chem. Indust. 1961, 289 (1961).
  2. Metabolic products of fungi. XXV. Synthesis of rubrofusarin and its derivatives: S. Shibata, et al.; Chem. Pharm. Bul.l (Tokyo) 15, 1757 (1967)
  3. The biosynthesis of rubrofusarin, a polyketide naphthopyrone from Fusarium culmorum: F.J. Leeper & J. Staunton; J. Chem. Soc. Perkin 1 1984, 2919 (1984).
  4. Biometic syntheses of the polyketide fungal metabolites alternariol and rubrofusarin: C. Abell, et al.; J. Chem. Soc. Chem. Comm. 1986, 15 (1986)
  5. Phenolic constituents of Cassia seeds and antibacterial effect of some naphthalenes and anthraquinones on methicillin-resistant St. aureus: T. Hatano, et al.; Chem. Pharm. Bull. 47, 1121 (1999)
  6. A new naphthopyrone derivative from Cassia quinquangulata and structural revision of quinquangulin and its glycosides: X.C. Li, et al.; J. Nat. Prod. 64, 1153 (2001)
  7. Antimycobacterial naphthopyrones from Senna oblique: J.G. Graham, et al.; J. Nat. Prod. 67, 225 (2004)
  8. Estrogenic and anti-estrogenic activities of Cassia tora phenolic constituents: A.M. El-Halawany, et al.; Chem. Pharm. Bull. (Tokyo) 55, 1476 (2007)
  9. In vitro cytotoxicity of fungal spoiling maize silage: R.R. Rasmussen, et al.; Food Chem. Toxicol. 49, 31 (2010)
  10. Three dimeric naphtho-γ-pyrones from the mangrove endophytic fungus Aspergillus tubingensis isolated from Pongamia pinnata: H.-B. Huang, et al.; Planta Med 76, 1888 (2010)
  11. Two novel classes of enzymes are required for the biosynthesis of aurofusarin in Fusarium graminearum: R.J.N. Frandsen, et al.; J. Biol. Chem. 286, 10419 (2011)
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