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Zearalenone

BVT-0394-M005 5 mg $50.00
BVT-0394-M025 25 mg $175.00
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Additional Information

Product Data
Synonyms Toxin F2; BRN 1350216; FES; NCI-C50226; Zenone
Properties
Formula C18H22O5
MW 318.4
Merck Index 13: 10169
CAS 17924-92-4
Source/Host Chemicals Isolated from Fusarium graminearum.
Purity ≥98% (HPLC)
Appearance Off-white solid.
Solubility Soluble in DMSO, methanol or acetone.
Identity Determined by 1H-NMR and UV.
Origin Manufactured by BioViotica.
InChi Key MBMQEIFVQACCCH-QBODLPLBSA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Documents
MSDS Download Document Download

Product Description

  • Resorcylic acid lactone.
  • Mycotoxin.
  • Regulator of fungal morphogenesis.
  • Mycoestrogen with anabolic and uterotrophic activity.
  • Ecdysteroid antagonist.
  • Gonadotropin inhibitor.
  • Interleukin antagonist.
  • Apoptosis inducer.
  • Analytical standard in food industry.

Product References

  1. The structure of zearalenone: W. H.  Urry, et al.; Tetrahedron Lett. 1966, 3109 (1966)
  2. Physicochemical data for some selected mycotoxins: A E. Pohland, et al.; Pure Appl. Chem. 54, 2219 (1982)
  3. Zearalenone: K. Panneerselvam, et al.; Acta Cryst. C52, 3095 (1996)
  4. The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor: X. Ding, et al.; Toxicol. Sci. 91, 448 (2006)
  5. Trace mycotoxin analysis in complex biological and food matrices by liquid chromatography-atmospheric pressure ionisation mass spectrometry: P. Zollner & B. Mayer-Helm; J. Chromatogr. A 1136, 123 (2006)
  6. The PKS4 gene of Fusarium graminearum is essential for zearalenone production: E. Lysoe, et al; Appl. Environ. Microbiol. 72, 3924 (2006)
  7. Chemistry and biology of resorcyclic acid lactones: N. Winssinger & S. Barluenga; Chem. Commun. 2007, 22 (2007)
  8. Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: an oestrogenic mycotoxin: A. Zinedine, et al.; Food Chem. Toxicol. 45, 1 (2007)
  9. Biomimetic synthesis of resorcylate natural products utilizing late stage aromatization: concise total syntheses of the marine antifungal agents 15G256ι and 15G256β: I. Navarro, et al.; JACS 130, 10293 (2008)
  10. Effects of exposure to zearalenone on porcine oocytes and sperm during maturation and fertilization in vitro: R. Sambuu, et al.; J. Reprod. Dev. 57, 547 (2011)
  11. Fusarium graminearum mycotoxins and their biosynthetic genes: H. Son & Y.-W. Lee; Mycotoxins 62, 29 (2012)
  12. Zearalenone induces apoptosis and necrosis in porcine granulose cells via a caspase-3- and caspase-9-dependent mitochondrial signaling pathway: L. Zhu, et al.; J. Cell. Physiol. 227, 1814 (2012)
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