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Aranciamycin

BVT-0364-C500 500 µg $130.00
BVT-0364-M001 1 mg $220.00
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Additional Information

Properties
Formula C27H28O12
MW 544.5
CAS 72389-06-1
Source/Host Chemicals Isolated from Streptomyces echinatus.
Purity ≥98% (HPLC)
Appearance Yellow to orange solid.
Solubility Soluble in DMSO.
Identity Determined by 1H-NMR.
Origin Manufactured by BioViotica.
InChi Key PGCZNTNNZCKKFG-XXHKFMCWSA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
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Product Description

  • Antibiotic.
  • Similar to steffimycin.
  • Active against Gram-positive bacteria.
  • Clostridium histolyticum collagenase inhibitor.
  • Antitumor compound.

Product References

  1. Aranciamycin: W. Keller-Schierlein, et al.; Helv. Chim. Acta 53, 779 (1970)
  2. Inhibition of collagenase by aranciamycin and aranciamycin derivatives: M. Bols, et al.; J. Med. Chem. 35, 2768 (1992)
  3. Structure of the anthracycline antibiotic aranciamycin: K. Schmidt-Bäse, et al.; Acta Cryst. C 49, 250 (1993)
  4. Cloning and heterologous expression of the aranciamycin biosynthetic gene cluster revealed a new flexible glycosyltransferase: A. Luzhetskyy, et al.; ChemBioChem 8, 599 (2007)
  5. Aranciamycin analogs generated by combinatorial biosynthesis show improved antitumor activity: A. Luzhetskyy, et al.; Appl. Microbiol. Biotechnol. 80, 15 (2008).
  6. Aranciamycin anhydride, a new anthracycline-type antibiotic isolated from Streptomyces sp. Tü 6384: J. Nachtigall, et al.; J. Antibiot. 63, 397 (2010)
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