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Elasnin

BVT-0342-M001 1 mg $130.00
BVT-0342-M005 5 mg $390.00
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Additional Information

Product Data
Synonyms 3,5-Dibutyl-4-hydroxy-6-(6-oxoundecan-5-yl)-2H-pyran-2-one
Properties
Formula C24H40O4
MW 392.6
CAS 68112-21-0
Source/Host Chemicals Isolated from Streptomyces sp.
Purity ≥98% (HPLC)
Appearance Tan to brown viscous liquid.
Solubility Soluble in DMSO (5 mg/ml), methanol (5 mg/ml) or methylene chloride.
Identity Determined by 1H-NMR.
Origin Manufactured by BioViotica.
InChi Key SNSPVFCYLPZTRZ-UHFFFAOYSA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry. Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Documents
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Product Description

  • Inhibitor of human leukocyte elastase (IC50 = 1.3 μg/ml), different other elastases and chymotrypsin (IC50 = 82 μg/ml).

Product References

  1. Elasnin, a new human granulocyte elastase inhibitor produced by a strain of Streptomyces.: S. Omura, et al.; BBRC 83, 704 (1978)
  2. Isolation and characterization of elasnin, a new human granulocyte elastase inhibitor produced by a strain of Streptomyces: H. Ohno, et al.; J. Antibiot. 31, 1116 (1978)
  3. Inhibition of human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin by elasnin and other 4-hydroxy-2-pyrones.: R.W. Spencer, et al.; J. Med. Chem. 28, 1828 (1985)
  4. Inhibition of human sputum elastase by substituted 2-pyrones.: L. Cook, et al.; J. Med. Chem. 30, 1017 (1987)
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