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BioViotica
Elasnin
As low as
CHF 155.00
In stock
Only %1 left
BVT-0342-M0011 mgCHF 155.00
BVT-0342-M0055 mgCHF 470.00
Specifications / Handling
| Product Details | |
|---|---|
| Synonyms | 3,5-Dibutyl-4-hydroxy-6-(6-oxoundecan-5-yl)-2H-pyran-2-one |
| Product Type | Chemical |
| Properties | |
| Formula |
C24H40O4 |
| MW | 392.6 |
| CAS | 68112-21-0 |
| Source/Host Chemicals | Isolated from Streptomyces sp. |
| Purity Chemicals | ≥97% (HPLC) |
| Appearance | Tan to brown viscous liquid. |
| Solubility | Soluble in DMSO (5 mg/ml), methanol (5 mg/ml) or methylene chloride. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | SNSPVFCYLPZTRZ-UHFFFAOYSA-N |
| Smiles | CCCCCC(=O)C(CCCC)C1=C(CCCC)C(O)=C(CCCC)C(=O)O1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light when in solution. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| Safety Data Sheet |
Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Scientific Background Information
Product Description
- Inhibitor of human leukocyte elastase (IC50 = 1.3 μg/ml), different other elastases and chymotrypsin (IC50 = 82 μg/ml).
Product-specific References
- Elasnin, a new human granulocyte elastase inhibitor produced by a strain of Streptomyces.: S. Omura, et al.; BBRC 83, 704 (1978)
- Isolation and characterization of elasnin, a new human granulocyte elastase inhibitor produced by a strain of Streptomyces: H. Ohno, et al.; J. Antibiot. 31, 1116 (1978)
- Inhibition of human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin by elasnin and other 4-hydroxy-2-pyrones.: R.W. Spencer, et al.; J. Med. Chem. 28, 1828 (1985)
- Inhibition of human sputum elastase by substituted 2-pyrones.: L. Cook, et al.; J. Med. Chem. 30, 1017 (1987)
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