BioViotica

Pimprinine

Name: Pimprinine
Brand: BioViotica
SKU: BVT-0297
Price: 155.00 CHF
Availability: InStock

As low as CHF 155.00

In stock

Only %1 left

BVT-0297-M0011 mgCHF 155.00

BVT-0297-M0055 mgCHF 470.00

Specifications / Handling

More Information
Product Details
Synonyms	3-(2-Methyl-5-oxazolyl)-1H-indole; Antibiotic WS-30581C; NSC80793; 5-(3-Indoyl)-2-methyloxazole
Product Type	Chemical
Properties
Formula	C₁₂H₁₀N₂O
MW	198.2
CAS	13640-26-1
Source/Host Chemicals	Isolated from Streptomyces sp.
Purity Chemicals	≥98% (HPLC, NMR)
Appearance	Pale yellow to beige powder.
Solubility	Soluble in DMSO, methanol or acetone.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by BioViotica.
InChi Key	WZJPGCHCOHYLMB-UHFFFAOYSA-N
Smiles	CC1=NC=C(O1)C1=CNC2=CC=CC=C12
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.
Documents
Safety Data Sheet	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product Description

Indole alkaloid.
Monoamine oxidase inhibitor (MAOI).
Antiepileptic (anticonvulsant) compound.
Inhibitor of platelet aggregation and thromboxane A2 synthesis.
Weak antifungal and antituberculosis activity. Useful as lead structure for potent antifungal substances.

Product-specific References

The structure and synthesis of pimprinine: B.S. Joshi, et al.; Tetrahedron 19, 1437 (1963)
Pimprinine in the treatment of hyperkinetic diseases: M.J. Narasimhan Jr. & V.G. Ganla; Hindustan Antibiot. Bull. 9, 138 (1967)
Monoamine oxidase inhibitors isolated from fermented broths: T. Takeuchi, et al.; J. Antibiot. 26, 162 (1973)
Studies on new antiplatelet agents, WS-30581 A and B: K. Umehara, et al.; J. Antibiot. 10, 1153 (1984)
Pimprinine, an extracellular alkaloid produced by Streptomyces CDRIL-312: fermentation, isolation and pharmacological activity: S.R. Naik, et al.; J. Biotechnol. 88, 1 (2001)
Antimalarial and antituberculosis substances from Streptomyces sp. BCC26924: C. Intaraudom, et al.; Tetrahedron 67, 7593 (2011)
Synthesis and fungicidal activity of novel pimprinine analogues: M.-Z. Zhang, et al.; Eur. J. Med. Chem. 53, 283 (2012)

Call	+41 61 926 6040
Fax	+41 61 926 6049