BioViotica

Manumycin B

Name: Manumycin B
Brand: BioViotica
SKU: BVT-0264
Price: 115.00 CHF
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BVT-0264-M0011 mgCHF 115.00

Specifications / Handling

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Product Details
Synonyms	UCF1A; N98-1272A
Product Type	Chemical
Properties
Formula	C₂₈H₃₄N₂O₇
MW	510.6
CAS	139023-58-8
Source/Host Chemicals	Isolated from Streptomyces parvulus.
Purity Chemicals	≥98% (HPLC)
Appearance	Yellow to brown powder.
Solubility	Soluble in DMSO, methanol or chloroform.
Identity	Determined by ¹H-NMR and UV.
Declaration	Manufactured by BioViotica.
InChi Key	ZGICGDCGECBVTD-LOWJZYKPSA-N
Smiles	CCCC[C@@H](C)\C=C(/C)C(=O)NC1=C[C@@](O)(\C=C\C=C\C=C\C(=O)NC2=C(O)CCC2=O)[C@@H]2O[C@@H]2C1=O
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	After reconstitution protect from light at -20°C. Protect from light.
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C.
Documents
Safety Data Sheet	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product Description

Product-specific References

New compounds of the manumycin group of antibiotics and a facilitated route for their structure elucidation: I. Sattler, et al.; J. Org. Chem. 58, 6583 (1993)
Identification of ras farnesyltransferase inhibitors by microbial screening: M. Hara, et al.; PNAS 90, 2281 (1993)
TMC-1 A, B, C and D, new antibiotics of the Manumycin group produced by Streptomyces sp.: J. Kohno, et al.; J. Antibiot. 49, 1212 (1996)
EI-1511-3, -5 and EI-1625-2, novel interleukin-1 beta converting enzyme inhibitors produced by Streptomyces sp. E-1511 and E-1625. III. Biochemical properties of EI-1511-3, -5 and EI-1625-2: T. Tanaka, et al.; J. Antibiot. 49, 1085 (1996)
The manumycin-group metabolites: I. Sattler, et al.; Nat. Prod. Rep. 15, 221 (1998) (Review)
The first total synthesis of a type II manumycin antibiotic, (+)-TMC-1 A: the total syntheses of (-)-LL-C10037β and(+)-manumycin B: J.J. Cronjé Grové, et al.; Chem. Commun. 1999, 421 (1999)
Isolation and characterization of N98-1272 A, B and C, selective acetylcholinesterase inhibitors from metabolites ofan actinomycete strain: Z.-H. Zheng, et al.; J. Enzyme Inh. Med. Chem. 22, 43 (2007)
Inhibition of Pro-Inflammatory Cytokines by Metabolites of Streptomycetes—A Potential Alternative to Current Anti-Inflammatory Drugs? J. Hrdy, et al.; Microorg. 8, 621 (2020)

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