BioViotica

Chalcomycin

Name: Chalcomycin
Brand: BioViotica
SKU: BVT-0263
Price: 215.00 CHF
Availability: InStock

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BVT-0263-C500500 µgCHF 130.00

BVT-0263-M0011 mgCHF 215.00

Specifications / Handling

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Product Details
Synonyms	Aldgamycin D; NSC 150439
Product Type	Chemical
Properties
Formula	C₃₅H₅₆O₁₄
MW	700.8
CAS	20283-48-1
Source/Host Chemicals	Isolated from Streptomyces bikiniensis.
Purity Chemicals	≥96% (HPLC)
Appearance	Beige solid.
Solubility	Soluble in DMSO or acetone.
Identity	Determined by ¹H-NMR and UV.
Declaration	Manufactured by BioViotica.
InChi Key	KLGADJPDTCIJLO-GQVCZQSUSA-N
Smiles	CO[C@@H]1CC(C)O[C@@H](O[C@H]2[C@@H](C)C[C@](C)(O)C(=O)\C=C\[C@H]3O[C@H]3[C@H](CO[C@@H]3OC(C)[C@@H](O)[C@H](OC)C3OC)[C@@H](C)OC(=O)\C=C\[C@@H]2C)C1O
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Documents
Safety Data Sheet	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product Description

Product-specific References

The structure of chalcomycin: P.W.K. Woo, et al.; JACS 86, 2726 (1964)
Cross resistance pattern towards anticancer drugs of a human carcinoma multidrug-resistant cell line: R.S. Gupta, et al.; Br. J. Cancer 58, 441 (1988)
Chalcomycin: single-crystal x-ray crystallographic analysis; biosynthetic and stereochemical correlations with other polyoxo macrolide antibiotics: P.W.K. Woo & J.R. Rubin; Tetrahedron 52, 3857 (1996)
Chalcomycin B, a new macrolide antibiotic from the marine isolate Streptomyces sp. B7064: R.N. Asolkar, et al.; J. Antibiot. (Tokyo) 55, 893 (2002)
Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: Novel features of an unusual ketolide produced through expression of the chm polyketide synthase in streptomyces fradiae: S.L. Ward, et al.; Antimicrob. Agents Chemoth. 48, 4703 (2004)
Aldgamycin I, an antibacterial 16-membered macrolide from the abandoned mine bacterium, Streptomyces sp. KMA-001: J.-S. Park, et al.; J. Antibiot. (Tokyo) 62, 171 (2009)
Imaging secondary metabolism of Streptomyces sp. Mg1 during cellular lysis and colony degradation of competing Bacillus subtilis: S.R. Barger, et al.; Antonie Van Leeuwenhoek 102, 435 (2012)

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