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Chrysomycin A

BVT-0099-C250 250 µg $140.00
BVT-0099-M001 1 mg $350.00
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Additional Information

Product Data
Synonyms Chrysomycin V; Virenomycin V
Properties
Formula C28H28O9
MW 508.5
CAS 82196-88-1
Source/Host Chemicals Isolated from Streptomyces sp.
Purity ≥98% (HPLC)
Appearance Yellow to greenish solid.
Solubility Soluble in DMSO or dimethylformamide; slightly soluble in 100% ethanol or methanol.
Identity Determined by 1H-NMR.
Origin Manufactured by BioViotica.
InChi Key OMDANBMKOUVKAG-WZNMFJNZSA-N
Product Type Chemical
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
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Product Description

  • Antibiotic.
  • Topoisomerase II inhibitor.
  • Mediates a unique cross-linking reaction between DNA and histidine H3.
  • Anti-neoplastic.
  • Photosensitizing compound.
  • Antitumor compound against human cell lines.

Product References

  1. Chrysomycin: a new antibiotic substance for bacterial viruses: F. Strelitz, et al.; J. Bacteriol. 69, 280 (1955)
  2. The chemistry of the antibiotics chrysomycin A and B. Antitumor activity of chrysomycin A: U. Weiss, et al.; J. Antibiot. 35, 1194 (1982)
  3. Biochemical characterisation of elsamicin and other coumarin-related antitumour agents as potent inhibitors of human topoisomerase II: A. Lorico & B.H. Long; Eur. J. Cancer 29A, 1985 (1993)
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