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Isatropolone A

BVT-0080-M001 1 mg $120.00
BVT-0080-M005 5 mg $360.00
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Additional Information

Properties
Formula C24H24O9
MW 456.5
Source/Host Chemicals Isolated from Streptomyces rubiginosohelvolus Gö66.
Purity ≥98% (HPLC)
Appearance Orange powder.
Solubility Soluble in DMSO, chloroform or dichloromethane.
Identity Determined by 1H-NMR.
Origin Manufactured by BioViotica.
InChi Key GPTONKSPQNETHU-DLIRKSNVSA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Documents
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Product Description

  • Antileishmanial agent. Active against Leishmania donovani, the causative agent of visceral leishmaniasis. Showed no activity against intracellular Leishmania.
  • Amine-reactive fluorescent compound.
  • Cytostatic.
  • Weak cytotoxic (3-10 μM).

Product References

  1. Isolierung, Strukturaufklärung und Biosynthese der Isatropolone aus Streptomyces sp. Gö66: N. Pöhlmann; PhD Thesis; Univ. Göttingen, Cuvillier Verlag, Page 1-136 (2004) [ISBN 3-86537-286-4]
  2. Structure and biosynthesis of isatropolones, bioactive amine-scavenging fluorescent natural products from Streptomyces Gö66: X. Cai, et al.; Angew. Chem. Int. Ed. Engl. 56, 4945 (2017)
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