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Benadrostin

BVT-0079-C500 500 µg $75.00
BVT-0079-M001 1 mg $120.00
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Additional Information

Product Data
Synonyms 8-Hydroxy-2H-1,3-benzoxazine-2,4(3H)-dione
Properties
Formula C8H5NO4
MW 179.1
CAS 117241-60-8
RTECS DM3130000
Source/Host Chemicals Isolated from Streptomyces rubiguiosohelvolus Gö66.
Purity ≥98% (HPLC; NMR)
Appearance White to off-white solid.
Solubility Soluble in DMSO, methanol or chloroform.
Identity Determined by 1H-NMR.
Origin Manufactured by BioViotica.
InChi Key BQIRLGRTNUTGAT-UHFFFAOYSA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
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Product Description

  • Poly(ADP-ribose) polymerase (PARP) inhibitor.

Product References

  1. Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. I. Taxonomy, production, isolation, physicochemical properties and biological activities: T. Aoyagi, et al.; J. Antibiot. 41, 1009 (1988)
  2. Benadrostin, new inhibitor of poly(ADP-ribose) synthetase, produced by actinomycetes. II. Structure determination: S. Yoshida, et al.; J. Antibiot. 41, 1015 (1988)
  3. Effects of benadrostin, a poly(ADP-ribose) polymerase inhibitor, on apoptosis of HL-60 induced by 5-azacytidine: H. Tobe, et al.; Biosci. Biotechnol. Biochem. 61, 1603 (1997)
  4. New potent DPPH radical scavengers from a marine-derived actinomycete strain USF-TC31: Y. Sugiyama, et al.; Biosci. Biotechnol. Biochem. 73, 2731 (2009)
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