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CJ-21058

BVT-0064-M001 1 mg $120.00
BVT-0064-M005 5 mg $360.00
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Additional Information

Product Data
Synonyms (5R,Z)-3-(Hydroxy((1R,2S,6S,8aS)-1,3,6-trimethyl-2-((E)-prop-1-en-1-yl)-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl)methylene)-5-(hydroxymethyl)-1-methylpyrrolidine-2,4-dione
Properties
Formula C23H33NO4
MW 387.5
CAS 405072-57-3
Source/Host Chemicals Isolated from Phoma sp.
Purity ≥98% (HPLC)
Appearance Off-white solid.
Solubility Soluble in methylene chloride, DMSO or methanol.
Identity Determined by 1H-NMR.
Origin Manufactured by BioViotica.
InChi Key ZTPMRDYXXHRMRU-YLTLMIQISA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry. Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Documents
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Product Description

  • Antibiotic.
  • SecA inhibitor.
  • Antibacterial and antifungal.
  • Cytotoxic.
  • Methyl analog of equisetin.

Product References

  1. CJ-21,058, a new SecA inhibitor isolated from a fungus Y. Sugie, et al. J. Antibiot. 55, 25 (2002)
  2. Discovery of the first SecA inhibitors using structure-based virtual screening M. Li, et al. BBRC 386 839 (2008)
  3. Post-translational import of protein into the endoplasmic reticulum of atrypanosome: an in vitro system for discovery of anti-trypanosomal chemical entities B. Patham, et al. Biochem. J. 419, 507 (2009)
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