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Resistomycin

BVT-0036-M001 1 mg $95.00
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Additional Information

Product Data
Synonyms Geliomycin; Heliomycin; Itamycin; 3,5,7,10-Tetrahydroxy-1,1,9-trimethyl-1H-benzo-[cd]pyrene-2,6-dione
Properties
Formula C22H16O6
MW 376.4
CAS 20004-62-0
RTECS DJ6350000
Source/Host Chemicals Isolated from Streptomyces sp.
Purity ≥98% (HPLC)
Appearance Yellow to orange solid.
Solubility Soluble in DMSO or methanol.
Identity Determined by 1H-NMR.
Origin Manufactured by BioViotica.
InChi Key ABLACSIRCKEUOB-UHFFFAOYSA-N
Product Type Chemical
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
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Product Description

  • Antibacterial (Gram-positive and mycobacteria).
  • RNA polymerase inhibitor.
  • Apoptosis inducer.

Product References

  1. Effects of the antibiotic resistomycin on the synthesis of macromolecules: I. Haupt, et al.; Z. Allg. Mikrobiol. 156, 411 (1975)
  2. 3-Alkanoyl-5-hydroxymethyl tetronic acid homologues and resistomycin: new inhibitors of HIV-1 protease. I. Fermentation, isolation and biological activity: B.E. Roggo, et al.; J. Antibiot. 47, 136 (1994)
  3. Effects of polyphenolic anthrone derivatives, resistomycin and hypericin, on apoptosis in human megakaryoblastic leukemia CMK-7 cell line: Y. Shiono et al.; Z. Naturforsch. 57c, 923 (2002)
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