BioViotica

Aspyrone

Name: Aspyrone
Brand: BioViotica
SKU: BVT-0029
Price: 95.00 CHF
Availability: InStock

As low as CHF 95.00

In stock

Only %1 left

BVT-0029-M0011 mgCHF 95.00

BVT-0029-M0055 mgCHF 325.00

Specifications / Handling

More Information
Product Details
Synonyms	(5S,6R)-5-Hydroxy-6-methyl-3-((2S,3S)-3-methyl-oxiran-2-yl)-5,6-dihydro-2H-pyran-2-one
Product Type	Chemical
Properties
Formula	C₉H₁₂O₄
MW	184.2
CAS	17398-00-4
Source/Host Chemicals	Isolated from Aspergillus ochraceus.
Purity Chemicals	≥98% (HPLC)
Appearance	White to off-white solid.
Solubility	Soluble in DMSO, acetone or methanol.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by BioViotica.
InChi Key	RCAULRNMJFUWRP-HETMPLHPSA-N
Smiles	C[C@@H]1OC1C1=C[C@H](O)[C@@H](C)OC1=O
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from moisture.
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Documents
Safety Data Sheet	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Scientific Background Information

Product Description

Antibiotic.
Shows nematicidal, insecticidal, antibacterial and antifungal activity.
Related to asperlactone and aspinonene.

Product-specific References

A new metabolite of Aspergillus melleus: S.D. Mills & W.B. Turner; J. Chem. Soc. (C) 2242 (1967)
Production of 3-(1,2-epoxypropyl)-5,6-dihydro-5-hydroxy-6-methylpyran-2-one by Aspergillus ochraceus Wilhelm: J.H. Moore, et al.; J. Agr. Food Chem. 22, 697 (1974)
J.S.E. Holker, et al.; J.C.S. Perkin Trans. 1, 1397 (1981)
Biosynthesis of aspyrone, a metabolite of Aspergillus melleus: advanced precursor studies to identify the product of the polyketide synthase: J. Staunton & A.C. Sutkowski; J.C.S. Chem. Commun. 1108 (1991)
The polyketide synthase (PKS) of aspyrone biosynthesis: evidence for the enzyme bound intermediates from incorporation studies with N-acetylcysteamine thioesters in intact cells of Aspergillus melleus: J. Staunton & A.C. Sutkowski; J.C.S. Chem. Commun. 1110 (1991)
Biosynthesis of aspinonene, a branched pentaketide by Aspergillis ochraceus, related to aspyrone: J. Fuchser, et al.; J. Chem. Soc. Perkin Trans 1, 1663 (1995)
Effect of fungal metabolites and some derivatives against Tribolium castaneum (Herbst) and Nezara viridula (L.): M. Balcells, et al.; Pestic. Sci. 45, 319 (1995)
Synthesis of chiral aspyrone, a multi-functional dihydropyranone antibiotic: T. Sugiyama, et al.; Biosci. Biotech. Biochem. 59, 1921 (1995)
Aspyrone, a nematicidal compound isolated from the fungus, Aspergillus melleus: Y. Kimura, et al.; Biosci. Biotech. Biochem. 60, 1375 (1996)
Bactericidal and fungicidal activity of Aspergillus ochraceus metabolites and some derivatives: M. Torres, et al.; Pestic. Sci. 53, 9 (1998)
Aspinolide and aspinonene/aspyrone co-metabolites, new pentaketides produced by Aspergillus ochraceus: J. Fuchser & A. Zeeck; Liebigs Ann./Recueil|87 (1997)

Call	+41 61 926 6040
Fax	+41 61 926 6049