BioViotica

Reticulol

Name: Reticulol
Brand: BioViotica
SKU: BVT-0011
Price: 190.00 CHF
Availability: InStock

As low as CHF 90.00

In stock

Only %1 left

BVT-0011-C250250 µgCHF 90.00

BVT-0011-M0011 mgCHF 190.00

Specifications / Handling

More Information
Product Details
Synonyms	6,8-Dihydroxy-7-methoxy-3-methyl-1H-isochromen-1-one
Product Type	Chemical
Properties
Formula	C₁₁H₁₀O₅
MW	222.2
CAS	26246-41-3
Source/Host Chemicals	Isolated from Streptomyces sp.
Purity Chemicals	≥98% (HPLC)
Appearance	White to off-white solid.
Solubility	Soluble in DMSO, acetone or dimethylformamide.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by BioViotica.
InChi Key	LREZRXWUEZCZRU-UHFFFAOYSA-N
Smiles	COC1=C(O)C2=C(C=C(C)OC2=O)C=C1O
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Documents
Safety Data Sheet	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product Description

Antibiotic.
Cyclic adenosine 3',5'-monophosphate phosphodiesterase and topoisomerase I (Topo I) inhibitor.
Antitumor compound.
Potential antifood allergic agent. Decreased the rates of degranulation and histamine release.

Product-specific References

Reticulol, a new metabolic isocoumarin: L.A. Mitscher, et al.; Experientia 20, 258 (1964)
Isocoumarins from Streptomyces mobaraensis: M.A.W. Eaton and D.W. Hutchinson; Tetrahedron Lett. 12, 1337 (1971)
Reticulol, an inhibitor of cyclic adenosine 3', 5'-monophosphate phosphodiesterase: Y. Furutani, et al.; J. Antibiot. 28, 558 (1975)
Biosynthetic studies of reticulol, an isocoumarin, by ¹³C-NMR spectroscopy: Y. Furutani, et al.; Agric. Biol. Chem. 41, 1581 (1977)
Inhibition of cyclic nucleotide phosphodiesterases by reticulol: Y. Furutani, et al.; Agric. Biol. Chem. 41, 1587 (1977)
Reticulol, an inhibitor of cyclic nucleotide phosphodiesterases: Y. Furutani, et al.; Agric. Biol. Chem. 41, 989 (1977)
Antitumor efficacy of reticulol from Streptoverticillium against the lung metastasis model B16F10 melanoma. Lung metastasis inhibition by growth inhibition of melanoma: D.S. Lim, et al.; Chemotherapy 49, 146 (2003)
Topoisomerase I inactivation by reticulol and its in vivo cytotoxicity against B16F10 melanoma: D.S. Lim, et al.; Chemotherapy 49, 257 (2003)
An Efficient Synthesis of 8-Hydroxy-6,7-dimethoxy-3-methylisocoumarin (6-O-methylreticulol): A. Saeed and S. Ehsan; Chem. Heterocyc. Comp. 41, 1381 (2005)
Polyketides from the deep-sea-derived fungus Graphostroma sp. MCCC 3A00421 showed potent anti-food allergic activities: S. Niu, et al.; J. Agr. Food Chem. 14, 1369 (2018)

Call	+41 61 926 6040
Fax	+41 61 926 6049