BioViotica

Chartreusin

Name: Chartreusin
Brand: BioViotica
SKU: BVT-0005
Price: 155.00 CHF
Availability: InStock

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BVT-0005-M0055 mgCHF 155.00

Specifications / Handling

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Product Details
Synonyms	Lambdamycin
Product Type	Chemical
Properties
Formula	C₃₂H₃₂O₁₄
MW	640.6
Merck Index	14: 2045
CAS	6377-18-0
RTECS	FL7350000
Source/Host Chemicals	Isolated from Streptomyces chartreusis.
Purity Chemicals	≥98% (HPLC)
Appearance	Yellow solid.
Solubility	Soluble in acetone; insoluble in water.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by BioViotica.
InChi Key	PONPPNYZKHNPKZ-CIFTUGPDSA-N
Smiles	CO[C@H]1[C@@H](O)[C@@H](C)O[C@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](C)O[C@H]2OC2=CC=CC3=C2C2=C4C(C(=O)OC5=C4C(=C(C)C=C5)C(=O)O2)=C3O)[C@@H]1O
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	+4°C
Use/Stability	Stable for at least 1 year after receipt when stored at +4°C. After reconstitution protect from light at -20°C.
Documents
Safety Data Sheet	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product Description

Product-specific References

Chartreusin, a new antibiotic produced by Streptomyces chartreusis, a new species: B. E. Leach, et al.; J. Am. Chem. Soc. 75, 4011 (1953)
Chartreusin, a glycosidic antitumour antibiotic from Streptomyces: J.A. Beisler; Prog. Med. Chem. 19, 247 (1982) (Review)
Biochemical characterisation of elsamicin and other coumarin-related antitumour agents as potent inhibitors of human topoisomerase II: A. Lorico & B.H. Long; Eur. J. Cancer 14, 1985 (1993)
Chartreusin, elsamicin A and related anti-cancer antibiotics: J. Portugal; Curr. Med. Chem. Anticancer Agents 3, 411 (2003) (Review)
Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide: Z. Xu, et al.; Chem. Biol. 12, 579 (2005)
In silico studies on marine actinomycetes as potential inhibitors for glioblastoma multiforme: P. Kirubakaran, et al.; Bioinformation 6, 100 (2011)
Synthetic Remodeling of the chartreusin pathway to tune antiproliferative and antibacterial activities: N. Ueberschaar, et al.; JACS 135, 17408 (2013)
Rational design of an apoptosis-inducing photoreactive DNA intercalator: N. Ueberschaar, et al.; Angew. Chem. Int. Edit. 52, 6185 (2013)

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