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Pseurotin A

BVT-0003-M001 1 mg $90.00
BVT-0003-M005 5 mg $270.00
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Product Data
Synonyms (5S,8S,9R)-8-Benzoyl-2-((1S,2S,Z)-1,2-dihydroxyhex-3-en-1-yl)-9-hydroxy-8-methoxy-3-methyl-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione
Properties
Formula C22H25NO8
MW 431.4
CAS 58523-30-1
Source/Host Chemicals Isolated from Aspergillus fumigatus.
Purity ≥98% (HPLC)
Appearance White to off-white powder.
Solubility Soluble in methanol or ethyl acetate; poorly soluble in water.
Identity Determined by 1H-NMR.
Origin Manufactured by BioViotica.
InChi Key FCGCMRDADMTJIM-LFDIKFNASA-N
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
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Product Description

  • Antibiotic.
  • Chitin synthase inhibitor.
  • Cytotoxic.
  • Shows nematicidal activity.

Product References

  1. Novel neuritogenic activities of pseurotin A and penicillic acid: D. Komagata, et al.; J. Antibiot. 49, 958 (1996)
  2. Directed biosynthesis of fluorinated pseurotin A, synerazol and gliotoxin: Y. Igarashi, et al.; J. Antibiot. 57, 748 (2004)
  3. Fumiquinones A and B, nematicidal quinones produced by Aspergillus fumigatus: A. Hayashi, et al.; Biosci. Biotechnol. Biochem. 71, 1697 (2007)
  4. Identification of a hybrid PKS/NRPS required for Pseurotin A biosynthesis in the human pathogen Aspergillus fumigatus: S. Maiya, et al.; ChemBioChem 8, 1736 (2007)
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