Ancell

CD278 [ICOS] (human)-muIg Fusion Protein (R-PE)

CHF 945.00

In stock

ANC-517-05050 testsCHF 945.00

More Information
Product Details
Synonyms	ICOS; Inducible T Cell Costimulator; CRP1; CD28-related Protein-1; AILIM
Product Type	Protein
Properties
Source/Host	CHO cells
Crossreactivity	Human
Application	Flow Cytometry ELISA
Label/Conjugates	R-PE
Purity	≥95% (SDS-PAGE)
Formulation	50mM Sodium Phosphate pH 7.5, 500mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Protein Negative Control	MuIg Control Protein
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
Declaration	Manufactured by Ancell Corporation.
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Do not freeze. Protect from light.
Use/Stability	Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

The inducible costimulator CD278 (ICOS; T cell activation molecule H4) is similar to human CD28 (24% homology) and plays an analogous role in the T cell activation process. Each secondary signal from CD278 results in a discrete cytokine secretion profile displayed by the activated T cell. Both activation processes are effectively down regulated by CD152 (CTLA-4) engagement.

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