Ancell

anti-CD257 [BAFF] (human), mAb (ANC2H3) (R-PE)

CHF 455.00
In stock
ANC-266-050120 testsCHF 455.00
More Information
Product Details
Synonyms BAFF; Blys; TALL-1; B Cell Activating Factor; Tumor Necrosis Factor Ligand Superfamily Member 13B; TNFSF13B
Product Type Monoclonal Antibody
Properties
Clone ANC2H3
Isotype Mouse IgG1κ
Immunogen/Antigen Recombinant soluble human CD257(BAFF).
Label/Conjugates FITC
Application

ELISA
Flow Cytometry
Functional Application: Blocking

Crossreactivity Human
Formulation 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Isotype Negative Control

Mouse IgG1 Isotype Control (R-PE)

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by Ancell Corporation.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Do not freeze.
Protect from light.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF
Description

BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).

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