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NSC697923

AG-CR1-3519-M001 1 mg $20.00
AG-CR1-3519-M005 5 mg $55.00
AG-CR1-3519-M025 25 mg $160.00
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Additional Information

Product Data
Synonyms 2-(4-Methylphenyl)sulfonyl-5-nitrofuran
Properties
Formula C11H9NO5S
MW 267.3
CAS 343351-67-7
Purity ≥98% (NMR)
Appearance White solid.
Solubility Soluble in DMSO.
Identity Determined by 1H-NMR.
InChi Key GAUHIPWCDXOLCZ-UHFFFAOYAJ
Product Type Chemical
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
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Product Description

  • Selective Ub-conjugating enzyme (E2) complex Ubc13-Uev1A inhibitor. Inhibits the formation of the Ubc13~Ub conjugate.
  • NF-κB activation inhibitor.
  • Inhibits proliferation and survival of ABC-DLBCL and GCB-DLBCL (diffuse large B cell lymphoma) cells.

Product References

  1. Inhibition of proliferation and survival of diffuse large B-cell lymphoma cells by a small-molecule inhibitor of the ubiquitin-conjugating enzyme Ubc13-Uev1A: M. Pulvino, et al.; Blood 120, 1668 (2012)
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