AdipoGen Life Sciences

SAG Analog (LowTox)

CHF 295.00
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AG-CR1-3517-M0011 mgCHF 295.00
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Product Details
Synonyms Compound 10c; 3,4-Dichloro-N-(trans-4-(methylamino)cyclohexyl)-N-(3-pyridin-4-ylbenzyl)benzo[b]thiophene-2-carboxamide
Product Type Chemical
Properties
Formula

C28H27Cl2N3OS (trans-isomer)

MW 524.5
CAS 1401532-78-2
Purity Chemicals ≥98% (NMR)
Appearance White to light yellow solid.
Solubility Soluble in DMSO.
Identity Determined by 1H-NMR and MS.
InChi Key OBYJCKCGYTYXFN-HZCBDIJEBZ
Smiles [H][C@@]1(CC[C@@]([H])(CC1)N(CC1=CC=CC(=C1)C1=CC=NC=C1)C(=O)C1=C(Cl)C2=C(Cl)C=CC=C2S1)NC
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Store solutions at -20°C in the dark.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Cell permeable low toxicity Sonic hedgehog (Shh) agonist.
  • Cell permeable smoothened (Smo) agonist.
  • Potent activator of VEGF expression in vitro.
Product References
  1. Potent small molecule Hedgehog agonists induce VEGF expression in vitro: K. Seifert, et al.; Bioorg. Med. Chem. 20, 6465 (2012)
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