AdipoGen Life Sciences

BMS-3

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AG-CR1-2901-M0055 mgCHF 95.00
AG-CR1-2901-M02525 mgCHF 380.00

Specifications / Handling

More Information
Product Details
Synonyms N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2- yl)cyclopropanecarboxamide
Product Type Chemical
Properties
Formula

C17H12Cl2F2N4OS

MW 429.3
CAS 1338247-30-5
Purity Chemicals ≥98% (HPLC)
Appearance Off-white solid.
Solubility Soluble in DMSO (5mg/ml).
InChi Key YBGGBHCJSAEIAS-UHFFFAOYSA-N
Smiles ClC1=C(N2C(C3=CN=C(NC(C4CC4)=O)S3)=CC(C(F)F)=N2)C(Cl)=CC=C1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF Download PDF
Product Specification Sheet
Datasheet Download PDF Download PDF

Product-specific References

Description

Potent LIMK (Lim kinase) inhibitor. Has IC50 values of 5nM and 6nM for LIMK1 and LIMK2, respectively.

Product References
  1. Phenyl-substituted pyrimidine compounds useful as kinase inhibitors: S.T. Wrobelski, et al.; WO2006084017 (2006)
  2. Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors: P. Ross-Macdonald, et al.; Mol. Cancer Ther. 7, 3490 (2008)
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