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AdipoGen Life Sciences
SB366791
70
CHF
CHF 70.00
In stock
AG-CR1-0034-M0055 mgCHF 70.00
AG-CR1-0034-M02525 mgCHF 280.00
| Product Details | |
|---|---|
| Synonyms | N-(3-Methoxyphenyl)-4-chlorocinnamide |
| Product Type | Chemical |
| Properties | |
| Formula |
C16H14ClNO2 |
| MW | 287.8 |
| CAS | 472981-92-3 |
| Purity Chemicals | ≥99% (NMR) |
| Appearance | White to beige crystalline solid. |
| Solubility | Soluble in 100% ethanol (warm) or DMSO. |
| Other Product Data |
Solutions are stable for up to 3 months when stored at -20°C. |
| InChi Key | RYAMDQKWNKKFHD-JXMROGBWSA-N |
| Smiles | COC1=CC=CC(NC(=O)C=CC2=CC=C(Cl)C=C2)=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Potent and selective TRPV1 antagonist [1, 2].
- Glutamatergic synaptic transmission inhibitor [3].
Product References
- Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist: M.J. Gunthorpe, et al.; Neuropharmacology 46, 133 (2004)
- Effects of the novel TRPV1 receptor antagonist SB366791 in vitro and in vivo in the rat: A. Varga, et al.; Neurosci. Lett. 385, 137 (2005)
- TRPV1 antagonist, SB-366791, inhibits glutamatergic synaptic transmission in rat spinal dorsal horn following peripheral inflammation: S.C. Lappin, et al.; Eur. J. Pharmacol. 540, 73 (2006)
- Heat induces interleukin-6 in skeletal muscle cells via TRPV1/PKC/CREB pathways: S. Obi, et al.; J. Appl. Physiol. 122, 683 (2017)
- Heat induces myogenic transcription factors of myoblast cells via transient receptor potential vanilloid 1 (Trpv1): S. Obi, et al.; FEBS Open Bio (2018)