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AdipoGen Life Sciences
Corynesidone A
230
CHF
CHF 230.00
In stock
AG-CN2-0496-M0011 mgCHF 230.00
| Product Details | |
|---|---|
| Synonyms | 3,8-Dihydroxy-1,6-dimethyl-11H-dibenzo[b,e][1,4]dioxepin-11-one; 2-Deoxycorynesidone C |
| Product Type | Chemical |
| Properties | |
| Formula |
C15H12O5 |
| MW | 272.3 |
| CAS | 1159583-61-5 |
| Source/Host Chemicals | Isolated from Corynespora sp. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to off-white solid. |
| Solubility | Soluble in DMSO, ethanol or methanol. |
| Identity | Determined by 1H-NMR and MS. |
| InChi Key | KCAVPBLHZJMMLN-UHFFFAOYSA-N |
| Smiles | OC1=CC2=C(OC(C=C(O)C=C3C)=C3C(O2)=O)C(C)=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Potent antioxidant. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) scavenger.
- Anti-cancer and anti-inflammatory compound.
- Aromatase activity inhibitor.
- Moderate cytotoxic against selected cancer cell lines.
Product References
- Aromatase inhibitory, radical scavenging, and antioxidant activities of depsidones and diaryl ethers from the endophytic fungus Corynespora cassiicola L36: P. Chomcheon, et al.; Phytochem. 70, 407 (2009)
- Natural compounds with aromatase inhibitory activity - An update: M.J. Balunas & A.D. Kinghorn; Planta Med. 76, 1087 (2010)
- Inhibition of inflammatory mediators and reactive oxygen and nitrogen species by some depsidones and diaryl ether derivatives isolated from Corynespora cassiicola, an endophytic fungus of Gongronema latifolium leaves: F.B. Okoye, et al.; Immunopharmacol. Immunotoxicol. 35, 662 (2013)
- Naphthalenones and depsidones from a sponge-derived strain of the fungus Corynespora cassiicola: D.L. Zhao, et al.; Molecules 21, 160 (2016)