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AdipoGen Life Sciences
Procyanidin A2
60
CHF
CHF 60.00
In stock
AG-CN2-0486-M0011 mgCHF 60.00
AG-CN2-0486-M0055 mgCHF 180.00
AG-CN2-0486-M02525 mgCHF 630.00
| Product Details | |
|---|---|
| Synonyms | (+)-Epicatechin-(4β-8,2β-O-7)-epicatechin; PCA2; Proanthocyanidin A2; PA2; Procyanidol A2; Procyanidin dimer A2 |
| Product Type | Chemical |
| Properties | |
| Formula |
C30H24O12 |
| MW | 576.5 |
| CAS | 41743-41-3 |
| Source/Host Chemicals | Isolated from grape seeds (Vitis vinifera L). |
| Purity Chemicals | ≥95% (NMR) |
| Appearance | Pale pink solid. |
| Solubility | Soluble in DMSO, 100% ethanol or methanol. Sparingly soluble in water (0.1 mg/ml). |
| Identity | Determined by 1H-NMR. |
| InChi Key | NSEWTSAADLNHNH-LSBOWGMISA-N |
| Smiles | OC1=CC(O)=C([C@H](C2=C(O[C@H](C3=CC(O)=C(O)C=C3)[C@H](O)C4)C4=C(O)C=C2O5)[C@@H](O)[C@@]5(C6=CC(O)=C(O)C=C6)O7)C7=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light. Protect from moisture and oxygen. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- A-Type proanthocyanidine.
- Potent antioxidant. Free radical scavenger and lipid peroxidation inhibitor.
- Potent low-density lipoprotein (LDL) oxidation inhibitor.
- Antidiabetic. Prevents islet cell apoptosis, hyperglycemia and type 2 diabetes through it's antioxidant properties.
- Antibacterial agent.
- Antiviral. Shown to inhibit viral replication of canine distemper virus (CDV).
- Glycosyltransferase B (GTFB) inhibitor.
Product References
- Phenolic constituents in the fruits of Cinnamomum zeylanicum and their antioxidant activity: G.K. Jayaprakasha, et al.; J. Agric. Food Chem. 54, 1672 (2006)
- Influence of cranberry phenolics on glucan synthesis by glucosyltransferases and Streptococcus mutans acidogenicity: S. Gregoire, et al.; J. Appl. Microbiol. 103, 1960 (2007)
- Influence of cranberry proanthocyanidins on formation of biofilms by Streptococcus mutans on saliva-coated apatitic surface and on dental caries development in vivo: H. Koo, et al.; Caries Res. 44, 116 (2010)
- Doubly linked, A-type proanthocyanidin trimer and other constituents of Ixora coccinea leaves and their antioxidant and antibacterial properties: T.O. Idowu, et al.; Phytochemistry 71, 2092 (2010)
- Inhibition of viral RNA synthesis in canine distemper virus infection by proanthocyanidin A2: L. Gallina, et al.; Antiviral Res. 92, 447 (2011)
- Flavonoids from Lindera glauca blume as low-density lipoprotein oxidation inhibitors: G.W. Huh, et al.; Nat. Prod. Res. 28, 831 (2014)
- Procyanidins from the stem wood of Machilus japonica and their inhibitory effect on LDL oxidation: H.J. Park, et al.; Arch. Pharm. Res. 37, 1403 (2014)
- Chemical composition, antioxidant and antinociceptive properties of Litchi chinensis leaves: R.C. Castellain, et al.; J. Pharm. Pharmacol. 66, 1796 (2014)
- Preventive effects of procyanidin A2 on glucose homeostasis, pancreatic and duodenal homebox 1, and glucose transporter 2 gene expression disturbance induced by bisphenol A in male mice: A. Ahangarpour, et al.; J. Physiol. Pharmacol. 67, 243 (2016)
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