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AdipoGen Life Sciences
Cyclosporin C
60
CHF
CHF 60.00
In stock
AG-CN2-0443-M0011 mgCHF 60.00
AG-CN2-0443-M0055 mgCHF 240.00
| Product Details | |
|---|---|
| Synonyms | Thr2-Cyclosporine; CsC |
| Product Type | Chemical |
| Properties | |
| Formula |
C62H111N11O13 |
| MW | 1218.6 |
| Merck Index | 14: 2752 |
| CAS | 59787-61-0 |
| Source/Host Chemicals | Isolated from Fusarium solani. |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | White solid. |
| Solubility | Soluble in 100% ethanol, acetone or ethyl acetate; insoluble in water. |
| InChi Key | JTOKYIBTLUQVQV-PODIXWLNSA-N |
| Smiles | [H][C@@]1([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)C(NC1=O)[C@@H](C)O)C(C)C |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Keep cool and dry. Protect from light. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Immunosuppressant. Calcineurin inhibitor with lower activity than Cyclosporin A (AG-CN2-0079).
- Antifungal.
- Antitumor.
Product References
- The structure of cyclosporin c: R. Traber, et al.; Helv. Chim. Acta 60, 1247 (1977)
- Cyclosporins: immunosuppressive agents with antitumor activity: W. Kreis & A. Soricelli; Experientia 35, 1506 (1979)
- Monitoring cyclosporine by HPLC with cyclosporin C as internal standard: P.M. Jones & K. Brune; Clin. Chem. 39, 168 (1993)
- Cyclosporin C is the main antifungal compound produced by Acremonium luzulae: M. Moussaif, et al.; Appl. Environ. Microbiol. 63, 1739 (1997)
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