AdipoGen Life Sciences

Boromycin

CHF 140.00
In stock
AG-CN2-0166-C250250 µgCHF 140.00
AG-CN2-0166-M0011 mgCHF 390.00
More Information
Product Details
Synonyms Antibiotic A 28829; Ivomycin; NSC216128
Product Type Chemical
Properties
Formula

C45H74BNO15

MW 879.9
CAS 34524-20-4
Source/Host Chemicals Isolated from Streptomyces sp.
Purity Chemicals ≥99% (TLC)
Appearance Off-white solid.
Solubility Soluble in DMSO, ethanol or methanol.
InChi Key OOBFYEMEQCZLJL-UWTAGDQBSA-O
Smiles [H][C@@]12O[B-]34O[C@@H](C(=O)O[C@@]([H])(C\C=C/CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@H](C)[C@@]1(O3)O5)[C@@H](C)OC(=O)[C@H]([NH3+])C(C)C)[C@]1(O4)O[C@@]([H])(CC[C@H]1C)C(C)(C)[C@H](O)CCC[C@@H]1C[C@H](OC2=O)[C@@H](C)O1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Boron-containing macrolide antibiotic [1].
  • Antibacterial [1].
  • Antiprotozoal (Plasmodium, Babesia) [2].
  • Anti-HIV compound [3,6].
  • Ca2+ homeostasis modulator [4].
  • Potentiator of bleomycin-induced anti-tumor activity [5].
  • Used as a chiral selector in capillary electrophoresis [7].
Product References
  1. Structure of boromycin: J.D. Dunitz, et al.; Helv. Chim. Acta 54, 1709 (1971)
  2. Antibiotic A 28829: V. Prelog, et al.; US Patent 3,769,418 (1973)
  3. Boromycin, an anti-HIV antibiotic: J. Kohno, et al.; Biosci. Biotechnol. Biochem. 60, 1036 (1996)
  4. The effect of boromycin on the Ca2+ homeostasis: B. Lakatos, et al.; Mol. Cell Biochem. 231, 15 (2002)
  5. Boromycin abrogates bleomycin-induced G2 checkpoint: M. Arai, et al.; J. Antibiot. 57, 662 (2004)
  6. Biologically active compounds of semi-metals: T. Rezanka & K. Sigler; Phytochem. 69, 585 (2008) (Review)
  7. Study on the use of boromycin as a chiral selector in capillary electrophoresis: V. Maier, et al.; J. Chromatogr. A. 1237, 128 (2012)
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