AdipoGen Life Sciences

n-Dodecyl-β-D-maltoside (ultrapure)

CHF 150.00
In stock
AG-CC1-0004-G0011 gCHF 150.00
AG-CC1-0004-G0055 gCHF 575.00
AG-CC1-0004-G02525 gCHF 2'300.00
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Product Details
Synonyms DDM; n-Dodecyl-β-maltoside; Lauryl-β-maltoside; Dodecyl-β-D-maltopyranoside
Product Type Chemical
Properties
Formula

C24H46O11

MW 510.6
CAS 69227-93-6
Purity Chemicals ≥99.5% (HPLC)
[α-Isomer <0.003% (HPLC)]
[n-Dodecanol <0.002% (HPLC)]
Appearance White crystal powder.
Solubility Soluble in water or 100% ethanol.
InChi Key NLEBIOOXCVAHBD-QKMCSOCLSA-N
Smiles CCCCCCCCCCCCOC1OC(CO)C(OC2OC(CO)C(O)C(O)C2O)C(O)C1O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Hygroscopic.
Protect from light and moisture.
Use/Stability Stable for at least 3 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Non-ionic detergent.
  • For functional solubilization, purification and crystallography of membrane proteins.
  • For the stabilization and activation of enzymes.
Product References
  1. Synthesis and properties of some α-D-alkyl glucosides and mannosides: apparent molal volumes and solubilization of nitrobenzene in water at 25°C: G.M. Brown, et al.; Can. J. Chem. 48, 2525 (1970)
  2. Detergent-mediated reconstitution of membrane proteins: J. Knol, et al.; Biochem. 37, 16410 (1998)
  3. Macromolecular Crystallography Protocols: S. Doublie; Methods Mol. Biol. 363, (2007)
  4. Detergents for the stabilization and crystallization of membrane proteins: G.G. Prive; Methods 41, 388 (2007)
  5. The use of detergents to purify membrane proteins; T. Arnold & D. Linke; Curr. Protoc. Protein Sci. Chapter 4: Unit 4.8.1-4.8.30 (2008)
  6. Expression, purification and in vitro functional reconstitution of the chemokine receptor CCR1: S.J. Allen, et al.; Prot. Expr. Purif. 66, 73 (2009)
  7. Structuring detergents for extracting and stabilizing functional membrane proteins: R. Matar-Merheb, et al.; PLoS One 6, e18036 (2011)
  8. Efficiency of detergents at maintaining membrane protein structures in their biologically relevant forms: D.V. Tulumello & C.M. Deber; Biochim. Biophys. Acta. 1818, 1351 (2012)
  9. High-throughput stability screening for detergent-solubilized membrane proteins: V. Kotov, et al.; Sci. Rep. 9, 10379 (2019)
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