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IL-38 (human) Matched Pair Detection Set

Reagents for 5 x 96-well plates
AG-46B-0007-KI01 1 Set INQ
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Product Data
Synonyms Interleukin-1 Family Member 10 theta; IL-1F10; FIL1θ; FKSG75; IL-1HY2; IL1-θ; Interleukin-1 HY2; Interleukin-1 Receptor Antagonist FKSG75
Properties
Application Quantitative ELISA
Specificity Recognizes human IL-38.
Crossreactivity Human
Quantity Contains sufficient materials to run ELISAs on 5 x 96-well plates.
Sensitivity 20pg/ml
Range 0.031 to 2ng/ml
Sample Type Cell Culture Supernatant, Serum
Assay Type Sandwich
Detection Type Colorimetric
Kit Contains 1 vial standard protein (1μg) (lyophilized) [STD]
1 vial coating antibody (270μl) [COAT]
1 vial detection antibody (60μl) [DET]
1 vial anti-IgG-HRP (10μg) (lyophilized) [HRP]
Product Type Kit
Shipping and Handling
Shipping BLUE ICE
Short Term Storage -20°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
Manual Download Document Download
MSDS Download Document Download
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Product Description

IL-38 (also called IL-1F10, and previously named IL1HY2, FIL1θ, or IL-1θ) is expressed in skin, tonsil, thymus, spleen, fetal liver, and salivary glands. The expression in a variety of immune tissues and similarity to IL-36Ra and IL-1Ra suggest a role of IL-38 in the inflammatory response. IL-38 binds to the IL-36R and exerts antagonistic effects similar to those of IL-36Ra.

Product References

  1. Interleukin-38 exerts antiinflammatory functions and is associated with disease activity in systemic lupus erythematosus: I. Rudloff, et al.; Arthr. Rheumatol. 67, 3219 (2015)
  2. Elevated plasma IL-38 concentrations in patients with acute ST-segment elevation myocardial infarction and their dynamics after reperfusion treatment: Y. Zhong, et al.; Med. Inflamm. 2015, ID490120 (2015)
  3. Aberrant expression of novel cytokine IL-38 and regulatory T lymphocytes in childhood asthma: M. Chu, et al.; Molecules 21, E933 (2016)
Standard Curve
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