Additional Information
| Product Data | |
|---|---|
| Synonyms | TNFRSF11A; ODFR; Osteoclast Differentiation Factor Receptor; CD265 |
| Properties | |
| Source/Host | HEK 293 cells |
| Sequence | Human RANK (aa 29-213) is fused at the C-terminus to the Fc portion of human IgG1. |
| Crossreactivity | Human, Mouse |
| Specificity | Binds to human and mouse RANKL. |
| Biological Activity | Inhibits human rhsRANKL biological functions. |
| MW | ~55kDa (SDS-PAGE) |
| Purity | ≥95% (SDS-PAGE) |
| Endotoxin Content | <0.1EU/μg purified protein (LAL test; Lonza). |
| Concentration | 1mg/ml after reconstitution. |
| Reconstitution | Reconstitute with 50μl sterile water. |
| Formulation | Lyophilized. Contains PBS. |
| Other Product Data | Swiss-Prot link O35305: RANK (mouse) (precursor) |
| Product Type | Protein |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. |
| Use/Stability | Stable for at least 6 months after receipt when stored at -20°C. |
| Documents | |
| MSDS |
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Product Description
RANK (TRANCE-R; CD265) is the receptor for RANKL/TRANCE/OPGL. It is essential for RANKL-mediated osteoclastogenesis and is involved in the regulation of interactions between T cells and dendritic cells.
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