AdipoGen Life Sciences

Omentin (human) (rec.)

CHF 220.00
In stock
AG-40B-0042-C01010 µgCHF 220.00
AG-40B-0042-30103 x 10 µgCHF 455.00
More Information
Product Details
Synonyms Galactofuranose-binding Lectin; Intestinal Lactoferrin Receptor; Intelectin-1; ITLN1; Endothelial Lectin HL-1; Omentin 1
Product Type Protein
Properties
Source/Host CHO cells
Sequence

Human omentin (aa 17-313) is fused at the N-terminus to a FLAG®-tag.

Crossreactivity Human
Biological Activity

Enhances glucose transport mediated by insulin.

MW ~38kDa
Purity ≥95% (SDS-PAGE)
Endotoxin Content <0.1EU/μg purified protein (LAL test; Lonza).
Concentration 0.1mg/ml after reconstitution.
Reconstitution Reconstitute with 100μl sterile water.
Formulation Lyophilized. Contains PBS.
Other Product Data

UniProt link Q8WWA0: Omentin (human) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
PBS containing at least 0.1% BSA should be used for further dilutions.
Use/Stability Stable for at least 6 months after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

Omentin (Intelectin-1) is highly expressed in omental adipose tissue, small intestine and various other tissues. Omentin has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylation in the absence and presence of insulin. It was suggested to play a role in the defense system against microorganisms by recognizing carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues.

Product References
  1. Ginsenoside Rd promotes omentin secretion in adipose through TBK1-AMPK to improve mitochondrial biogenesis via WNT5A/Ca2+ pathways in heart failure: S. Wan, et al.; Redox Biol. 60,  102610 (2023)
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